SCHEMBL509451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5226648	0.91	KCNH2 (0.48)	CYP1A2CYP2D6ALDH1A1TP53POLB
	SCHEMBL509432	0.81	BCHE (0.40)	ALDH1A1POLBHTTNPSR1SCN8A
	SCHEMBL509008	0.81	LMNA (0.38)	MEN1KMT2ASCN8AMAPTLMNA
	SCHEMBL508181	0.79	KCNH2 (0.47)	HTTSCN8ALMNA
	SCHEMBL5228883	0.78	KCNH2 (0.53)	CYP2D6ALDH1A1HTTMEN1KMT2A
	SCHEMBL5227097	0.78	KCNH2 (0.52)	CYP1A2CYP2D6TDP1HTTMAPK1
	SCHEMBL5229265	0.77	KCNH2 (0.51)	CYP2D6MEN1KMT2ASCN8A
	SCHEMBL5224371	0.76	KCNH2 (0.44)	MAPT
	SCHEMBL5229626	0.75	HTT (0.39)	ALDH1A1HTTMEN1KMT2A
	SCHEMBL508578	0.75	KCNH2 (0.53)	CYP2D6HTTSCN8ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.