Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139485 | 0.82 | SLC29A1 (0.46) | SLC29A1HTTKDM4ELMNAALDH1A1 | |
| SCHEMBL5025268 | 0.79 | SLC29A1 (0.43) | SLC29A1HTTKDM4ELMNAALDH1A1 | |
| SCHEMBL5025315 | 0.76 | HUWE1 (0.49) | HTTLMNAALDH1A1GAALRRK2 | |
| SCHEMBL5099543 | 0.75 | PDE4A (0.52) | HTTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL9159049 | 0.75 | HTT (0.61) | HTTKDM4ELMNAALDH1A1JAK3 | |
| SCHEMBL9690935 | 0.71 | RAB9A (0.61) | HTTKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL26200443 | 0.71 | CYP3A4 (0.45) | HTTKDM4ELMNACYP3A4ROCK2 | |
| SCHEMBL5026982 | 0.70 | ALDH1A1 (0.50) | HTTKDM4ELMNAALDH1A1POLB | |
| SCHEMBL5238861 | 0.69 | ADORA3 (0.55) | HTTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL18520451 | 0.68 | CYP3A4 (0.42) | HTTKDM4ELMNAPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |