Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17140706 | 0.80 | GPR119 (0.49) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL17848759 | 0.80 | GPR119 (0.56) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL17149526 | 0.80 | CCR5 (0.53) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL17767894 | 0.79 | GPR119 (0.48) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL318858 | 0.75 | CCR5 (0.75) | GPR119CCR5OPRD1OPRK1HSD17B10 | |
| SCHEMBL17140990 | 0.75 | CCR5 (0.49) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL21077995 | 0.75 | PLD2 (0.41) | ALOX15ATMOPRD1OPRK1MEN1 | |
| SCHEMBL19534281 | 0.75 | GPR119 (0.51) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL17777790 | 0.74 | GPR119 (0.50) | GPR119CCR5USP30TSHRALOX15 | |
| SCHEMBL17861595 | 0.74 | GPR119 (0.49) | GPR119USP30TSHRALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287478-A1 | Nociceptin Analogues and Uses Thereof | ZEALAND PHARMA A/S (DK) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287478-A1 | Nociceptin Analogues and Uses Thereof | OPRL1, NPSR1, OPRK1 | GPR119 420/4885CCR5 776/4885USP30 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.