SCHEMBL50986

SCHEMBL50986

O=S(=O)(Cl)c1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22494208 0.80
SCHEMBL50394 0.76
SCHEMBL3479000 0.71 ALDH1A1 (0.39)
SCHEMBL11567091 0.71 ALDH1A1 (0.35)
SCHEMBL11368885 0.71 L3MBTL1 (0.31)
SCHEMBL7665379 0.70
SCHEMBL11375532 0.69 LOXL2 (0.37)
SCHEMBL9435542 0.69 HTR6 (0.48)
SCHEMBL5376312 0.66 GAA (0.52)
SCHEMBL11564662 0.66 VCAM1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF LYSOWAY THERAPEUTICS INC (US) 2025-10-30 US disclosed
CN-114105959-B Triazole sulfonamide derivative and application thereof 东莞市东阳光农药研发有限公司 2025-01-10 CN disclosed
CN-118638140-A Oxo-substituted compounds 住友制药株式会社 2024-09-13 CN disclosed
CN-112135830-B Oxo-substituted compounds 住友制药株式会社 2024-06-14 CN disclosed
WO-2023235305-A2 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF Lysoway Therapeutics, Inc. (US) 2023-12-07 WO disclosed
US-20230287009-A1 OXO-SUBSTITUTED COMPOUND Sumitomo Pharma Co., Ltd. (JP) 2023-09-14 US disclosed
US-11702431-B2 Oxo-substituted compound Sumitomo Pharma Co., Ltd. (JP) 2023-07-18 US disclosed
WO-2022235091-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF 엠비디 주식회사 2022-11-10 WO disclosed
CN-114105959-A Triazole sulfonamide derivative and application thereof 东莞市东阳光农药研发有限公司 2022-03-01 CN disclosed
US-11066425-B1 Oxo-substituted compound SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2021-07-20 US disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
EP-0603415-A1 SULFAMOYLTRIAZOLE DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI CHEMICAL CORPORATION (JP) 1994-06-29 EP disclosed
EP-0439687-B1 Process for the preparation of alkane- and arenesulfonamides ATOCHEM NORTH AMERICA (US) 1993-12-29 EP disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
US-5258361-A Antigrowth agents biological ROHM AND HAAS COMPANY (US) 1993-11-02 US disclosed
US-5211739-A Herbicidal-1-(disubstituted carbamoyl or thiocarbamoyl)-1,2,4-triazol-3-yl sulfonates and thisulfonates ROHM AND HAAS COMPANY (US) 1993-05-18 US disclosed
US-5068427-A Dehydrohalogenation of ammonia with a halosulfonyl compound by condensation ATOCHEM NORTH AMERICA, INC. (US) 1991-11-26 US disclosed
EP-0439687-A1 Process for the preparation of alkane- and arenesulfonamides ATOCHEM NORTH AMERICA, INC. (US) 1991-08-07 EP disclosed
US-4148626-A Herbicidal agents THE BOOTS COMPANY LIMITED (GB) 1979-04-10 US disclosed
US-4128586-A Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols ALLIED CHEMICAL CORPORATION (US) 1978-12-05 US disclosed