SCHEMBL510774

SCHEMBL510774

C=C(C)C(=O)NCCCCN(CCC)CCC

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.47
DRD2 P14416 2/20 0.47
DRD4 P21917 1/20 0.47
PAOX Q6QHF9 2/20 0.38
EPHX1 P07099 5/20 0.37
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
PLA2G2A P14555 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM5A P29375 1/20 0.35
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182532 0.95 DRD2 (0.41) DRD3DRD2DRD4PAOXKDM4E
SCHEMBL291266 0.93 KDM5A (0.41) DRD3DRD2DRD4PAOXEPHX1
SCHEMBL3285678 0.93 EPHX1 (0.46) DRD3DRD2DRD4EPHX1ZDHHC20
SCHEMBL3280795 0.92 EPHX1 (0.48) EPHX1ZDHHC20ZDHHC2PLA2G2AKDM5A
SCHEMBL3280642 0.90 DNM1 (0.42) DRD3DRD2DRD4EPHX1ZDHHC20
SCHEMBL292986 0.88 DNM1 (0.45) EPHX1ZDHHC20ZDHHC2PLA2G2AKDM5A
SCHEMBL291199 0.88 DNM1 (0.45) EPHX1ZDHHC20ZDHHC2PLA2G2AKDM5A
SCHEMBL109907 0.88 PAOX (0.47) DRD3DRD2DRD4PAOXKDM4E
SCHEMBL135640 0.88 DNM1 (0.40) PAOXEPHX1KDM4EZDHHC20ZDHHC2
SCHEMBL292050 0.87 ALDH1A1 (0.39) DRD3DRD2DRD4KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969021-A1 HAIR CARE COMPOSITIONS COMPRISING POLYELECTROLYTE COMPLEXES FOR DURABLE BENEFITS Isp Investments Inc. (US) 2016-01-20 EP claimed
US-20160008257-A1 HAIR CARE COMPOSITIONS CONTAINING POLYELECTROLYTE COMPLEXES ISP INVESTMENTS INC. (US) 2016-01-14 US claimed
WO-2014144076-A1 HAIR CARE COMPOSITIONS COMPRISING POLYELECTROLYTE COMPLEXES FOR DURABLE BENEFITS ISP INVESTMENTS INC. (US) 2014-09-18 WO claimed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US claimed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US claimed
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-3347446-B1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2024-12-11 EP disclosed
US-11384316-B2 Stable laundry cleaning composition and method comprising a polyAPTAC-containing polymer ISP INVESTMENTS LLC (US) 2022-07-12 US disclosed
US-10722447-B2 Sprayable composition comprising high molecular weight charged polymer ISP INVESTMENTS LLC (US) 2020-07-28 US disclosed
US-20200224128-A1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2020-07-16 US disclosed
US-20190040172-A1 AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2019-02-07 US disclosed
EP-3411418-A1 AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE ISP Investments LLC (US) 2018-12-12 EP disclosed
EP-3347446-A1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP Investments LLC (US) 2018-07-18 EP disclosed
WO-1993025595-A1 CATIONIC POLYMER COMPOSITIONS ISP INVESTMENTS INC. (US) 1993-12-23 WO disclosed
EP-0430963-A4 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS 1991-11-21 EP disclosed
US-5045617-A Zwitterion terpolymers of a vinyl lactam, an amino alkyl acrylamide or acrylate, and a polymerizable carboxylic acid ISP INVESTMENTS INC. (US) 1991-09-03 US disclosed
EP-0430963-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. GAF CHEMICALS CORP (US) 1991-06-12 EP disclosed
US-4954343-A DRUG DELIVERY, (METH)ACRYLAMIDE WITH AMINO GROUP AS COPOLYMER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-09-04 US disclosed
US-4923694-A HAIR CONDITIONERS; (3-METHACRYLAMIDOPROPYL) TRIMETHYL AMMONIUM CHLORIDE-VINYLPYRROLIDONE COPOLYMER GAF CHEMICALS CORPORATION (US) 1990-05-08 US disclosed
WO-1990001920-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS GAF CHEMICALS CORPORATION (US) 1990-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008257-A1 HAIR CARE COMPOSITIONS CONTAINING POLYELECTROLYTE COMPLEXES POLR1C, PARG, HACD3 DRD3 1677/4885DRD2 2258/4885DRD4 2512/4885
US-20190040172-A1 AQUEOUS EMULSION POLYMERS AS RHEOLOGY MODIFIERS, COMPOSITIONS THEREOF, AND METHOD OF USE MUC1, ACP1, F12 DRD3 2015/4885DRD2 2475/4885DRD4 3022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.