Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931728 | 0.91 | THRA (0.42) | ALDH1A1CYP3A4KMT2APOLBTHRA | |
| SCHEMBL4934307 | 0.91 | CYP1A2 (0.37) | ALDH1A1CYP3A4KMT2APOLBTHRA | |
| SCHEMBL5110746 | 0.91 | RORC (0.40) | ALDH1A1CYP3A4KMT2ASENP5SENP2 | |
| SCHEMBL5117132 | 0.89 | THRB (0.49) | ALDH1A1CYP3A4TSHRMAPK1KMT2A | |
| SCHEMBL5105005 | 0.89 | TSHR (0.45) | ALDH1A1CYP3A4TSHRMAPK1KMT2A | |
| SCHEMBL4933128 | 0.89 | TRPA1 (0.41) | ALDH1A1CYP3A4TSHRKMT2APOLB | |
| SCHEMBL5118576 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRKMT2ASENP5 | |
| SCHEMBL5111499 | 0.88 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRKMT2ASENP5 | |
| SCHEMBL5106635 | 0.88 | THRA (0.38) | ALDH1A1CYP3A4KMT2APOLBTHRA | |
| SCHEMBL5119273 | 0.87 | KMT2A (0.40) | ALDH1A1CYP3A4KMT2ASENP5SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | ALDH1A1 2530/4885CYP3A4 2290/4885TSHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.