Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12072637 | 0.93 | USP30 (0.61) | ALDH1A1RAB9AGPR119KDM4EPKM | |
| SCHEMBL1412244 | 0.84 | ALDH1A1 (0.66) | ALDH1A1RAB9AL3MBTL1KMT2A | |
| SCHEMBL5198496 | 0.84 | ALDH1A1 (0.57) | ALDH1A1RAB9AEPHX1CA12CA1 | |
| SCHEMBL21088783 | 0.83 | EPHX1 (0.51) | ALDH1A1RAB9AEPHX1GPR119KDM4E | |
| SCHEMBL1412165 | 0.83 | HSD11B1 (0.58) | GAAUSP30KDM5A | |
| SCHEMBL1412162 | 0.83 | HSD11B1 (0.58) | GAAUSP30KDM5A | |
| SCHEMBL6038412 | 0.83 | ALDH1A1 (0.68) | ALDH1A1RAB9AEPHX1GAAMEN1 | |
| SCHEMBL20064368 | 0.82 | ALDH1A1 (0.54) | ALDH1A1RAB9AEPHX1GPR119CA12 | |
| SCHEMBL13199301 | 0.82 | KDM4E (0.68) | EPHX1GPR119KDM4EPKMUSP30 | |
| SCHEMBL6148210 | 0.82 | KDM4E (0.71) | ALDH1A1GPR119KDM4EPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022267470-A1 | SEH INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE COMPOSITION THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2022-12-29 | — | — | WO | disclosed |
| WO-2022267470-A1 | SEH INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE COMPOSITION THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2022-12-29 | — | — | WO | disclosed |
| CN-113402447-B | sEH inhibitor or pharmaceutically acceptable composition thereof, and preparation method and application thereof | 沈阳药科大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-108883185-B | Application of kappa opioid receptor agonist in preparation of medicine for treating pruritus caused by farnesol X receptor agonist | 江苏恒瑞医药股份有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113402447-A | sEH inhibitor or pharmaceutically acceptable composition thereof, and preparation method and application thereof | 沈阳药科大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-109422798-B | Free alkali crystal form of phenylpropionamide derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107098871-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-20200054594-A1 | PHARMACEUTICAL COMPOSITION CONTAINING MOR AGONIST AND KOR AGONIST, AND USES THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2020-02-20 | — | — | US | disclosed |
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| CN-100339376-C | Nitrogen-containing aromatic ring derivatives | EISAI CO LTD (JP) | 2007-09-26 | — | — | CN | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-7109219-B2 | Nitrogen-containing aromatic derivatives | EISAI CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| CN-1678607-A | Nitrogen-containing aromatic ring derivatives | EISAI CO LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054594-A1 | PHARMACEUTICAL COMPOSITION CONTAINING MOR AGONIST AND KOR AGONIST, AND USES THEREOF | OPRM1, OPRK1, OPRD1 | ALDH1A1 3029/4885RAB9A 2360/4885EPHX1 3452/4885 |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ALDH1A1 1501/4885RAB9A 878/4885EPHX1 2595/4885 |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ALDH1A1 1501/4885RAB9A 878/4885EPHX1 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.