Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.51 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 2/20 | 0.49 |
| ▸ | SELE | P16581 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722815 | 0.90 | SENP1 (0.48) | SLC1A2SLC1A1THRATHRBSENP5 | |
| SCHEMBL4354909 | 0.89 | THRA (0.61) | SLC1A2SLC1A1THRATHRBSENP5 | |
| SCHEMBL5110363 | 0.89 | THRB (0.60) | SLC1A2SLC1A1THRATHRBSENP5 | |
| SCHEMBL5111290 | 0.88 | CLCN2 (0.52) | THRATHRBSENP5SENP2SENP1 | |
| SCHEMBL4932778 | 0.86 | THRB (0.62) | THRATHRBSENP5SENP2SENP1 | |
| SCHEMBL5109827 | 0.86 | THRB (0.50) | THRATHRBSENP5SENP2SENP1 | |
| SCHEMBL4929427 | 0.86 | THRA (0.47) | THRATHRBSELPSELEMRGPRX4 | |
| SCHEMBL5104534 | 0.85 | THRA (0.52) | THRATHRBSENP5SENP2SENP1 | |
| SCHEMBL5117132 | 0.85 | THRB (0.49) | THRATHRBSENP5SENP2SENP1 | |
| SCHEMBL5117798 | 0.84 | THRB (0.48) | THRATHRBSENP5SENP2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | SLC1A2 2235/4885SLC1A1 1478/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.