Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722563 | 0.90 | SENP5 (0.46) | CLCN2USP2SENP5SENP2SENP1 | |
| SCHEMBL5110110 | 0.88 | SLC1A2 (0.51) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL4358744 | 0.88 | THRA (0.60) | CLCN2USP2SENP5SENP2SENP1 | |
| SCHEMBL5119092 | 0.88 | THRB (0.59) | USP2SENP5SENP2SENP1MEN1 | |
| SCHEMBL4929427 | 0.88 | THRA (0.47) | MEN1KMT2AMRGPRX4RAB9ANPC1 | |
| SCHEMBL5104534 | 0.87 | THRA (0.52) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL4930325 | 0.87 | THRA (0.45) | CLCN2KMT2AMRGPRX4THRATHRB | |
| SCHEMBL4932778 | 0.86 | THRB (0.62) | SENP5SENP2SENP1MEN1KMT2A | |
| SCHEMBL5104149 | 0.85 | THRB (0.44) | CLCN2MEN1KMT2AMRGPRX4THRA | |
| SCHEMBL5109969 | 0.84 | THRB (0.43) | CLCN2USP2SENP5SENP2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | CLCN2 1806/4885USP2 4150/4885SENP5 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.