Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 4/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114388 | 0.82 | GAA (0.46) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL4878985 | 0.79 | HTR1A (0.48) | HTR1A | |
| SCHEMBL7090551 | 0.75 | GAA (0.58) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL5117266 | 0.73 | GAA (0.53) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL3208122 | 0.73 | DRD2 (0.57) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL2162517 | 0.73 | DRD2 (0.64) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL5114515 | 0.72 | GAA (0.54) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL29046784 | 0.72 | DRD2 (0.56) | GAADRD2DRD3ADRA1ADRD4 | |
| SCHEMBL5110059 | 0.72 | DRD2 (0.48) | GAADRD2DRD3ADRA1ADRD4 | |
| Hydrochloric Acid SCHEMBL29046809 | 0.72 | DRD2 (0.55) | GAADRD2DRD3ADRA1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342015-B2 | Indole derivatives | H. LUNDBECK A/S (DK) | 2008-03-11 | — | — | US | claimed |
| US-20060258678-A1 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 2006-11-16 | — | — | US | claimed |
| EP-1399434-B1 | NOVEL INDOLE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2005-09-07 | — | — | EP | claimed |
| US-7342015-B2 | Indole derivatives | H. LUNDBECK A/S (DK) | 2008-03-11 | — | — | US | disclosed |
| US-20060258678-A1 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 2006-11-16 | — | — | US | disclosed |
| EP-1399434-B1 | NOVEL INDOLE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2005-09-07 | — | — | EP | disclosed |
| EP-1399434-A1 | NOVEL INDOLE DERIVATIVES | H. Lundbeck A/S (DK) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003002552-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258678-A1 | Novel indole derivatives | IDO1, TPH1, HTR5A | GAA 2020/4885DRD2 14/4885DRD3 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.