Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119270 | 0.83 | ADRB2 (0.34) | ADRB2ADRB1DRD2ABCB11PDE4A | |
| SCHEMBL5115576 | 0.81 | ADRB2 (0.47) | ADRB2ADRB1DRD2 | |
| SCHEMBL5709158 | 0.79 | ADRB2 (0.46) | ADRB2ADRB1DRD2ABCB11PDE4A | |
| SCHEMBL5115688 | 0.71 | ADRB2 (0.35) | ADRB2ADRB1DRD2 | |
| SCHEMBL4516416 | 0.68 | ADRB2 (0.78) | ADRB2ADRB1DRD2 | |
| SCHEMBL5120389 | 0.68 | ADRB2 (0.48) | ADRB2ADRB1DRD2 | |
| SCHEMBL7839794 | 0.67 | ABCB11 (0.59) | ADRB2ADRB1DRD2ABCB11PDE4A | |
| SCHEMBL4212051 | 0.67 | ADRB2 (0.71) | ADRB2ADRB1DRD2 | |
| SCHEMBL4212046 | 0.67 | ADRB2 (0.71) | ADRB2ADRB1DRD2 | |
| SCHEMBL5532802 | 0.66 | ADRB2 (0.57) | ADRB2ADRB1DRD2ABCB11PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402598-B2 | Arylethanolamine β2-adrenoreceptor agonist compounds | GLAXO GROUP LIMITED (GB) | 2008-07-22 | — | — | US | disclosed |
| US-20060111344-A1 | Arylethanolamine beta2-adrenoreceptor agonist compounds | GLAXO GROUP LIMITED (GB) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111344-A1 | Arylethanolamine beta2-adrenoreceptor agonist compounds | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885ADRB1 2/4885DRD2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.