Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934587 | 0.98 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ESRD5A2L3MBTL1 | |
| Bromide SCHEMBL3290361 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ESRD5A2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28147945 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ESRD5A2L3MBTL1 | |
| SCHEMBL485968 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1SRD5A2L3MBTL1HTT | |
| Bromide SCHEMBL231675 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SRD5A2L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL28502490 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TDP1SRD5A2L3MBTL1HTT | |
| SCHEMBL15440757 | 0.81 | SRD5A2 (0.52) | ALDH1A1KDM4ESRD5A2L3MBTL1HPGD | |
| Terephthalic Acid SCHEMBL8092882 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TDP1KDM4ESRD5A2SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL8434829 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TDP1KDM4ESRD5A2SMN1; SMN2 | |
| Benzoic Acid SCHEMBL592072 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TDP1KDM4ESRD5A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12597639-B2 | Solid polymer electrolyte for batteries | NATIONAL RESEARCH COUNCIL OF CANADA | 2026-04-07 | — | — | US | claimed |
| WO-2025043144-A1 | SIMULTANEOUS CHARACTERIZATION OF RNAS AND PROTEINS IN EXTRACELLULAR VESICLES AND LIPOPROTEINS | OHIO STATE INNOVATION FOUNDATION (US) | 2025-02-27 | — | — | WO | claimed |
| CN-110959221-B | Solid polymer electrolyte for battery | 加拿大国家研究委员会 | 2023-10-31 | — | — | CN | claimed |
| CN-112533980-B | General method for constructing hydrogels | 阿尔维勒公司 | 2023-10-20 | — | — | CN | claimed |
| EP-3814403-B1 | GENERIC METHOD FOR STRUCTURING HYDROGELS | ALVEOLE (FR) | 2022-12-28 | — | — | EP | claimed |
| US-11382868-B2 | Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same | ICURE PHARMACEUTICAL INC. (KR) | 2022-07-12 | — | — | US | claimed |
| US-20210277191-A1 | GENERIC METHOD FOR STRUCTURING HYDROGELS | ALVEOLE (FR) | 2021-09-09 | — | — | US | claimed |
| US-20210143475-A1 | Solid Polymer Electrolyte for Batteries | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2021-05-13 | — | — | US | claimed |
| EP-3814403-A1 | GENERIC METHOD FOR STRUCTURING HYDROGELS | Alveole (FR) | 2021-05-05 | — | — | EP | claimed |
| CN-112533980-A | General method of constructing hydrogels | 阿尔维勒公司 | 2021-03-19 | — | — | CN | claimed |
| US-20050214479-A1 | Compound for optical materials and methods of fabrication | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-09-29 | — | — | US | claimed |
| US-6403284-B1 | EXPOSURE TO LIGHT; CURING; SURFACE TREATMENT AND IMPREGNATION WITH HYDROGEN-ABSTRACTING AGENT; RADIATION TO REMOVE TACKINESS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2002-06-11 | — | — | US | claimed |
| US-5863650-A | Interfacial coatings | BIOENGINEERED MATERIALS, INC. (US) | 1999-01-26 | — | — | US | claimed |
| US-5824716-A | ULTRAVIOLET RADIATION CURABLE AQUEOUS LATEX OF PHOTOINITIATOR AND DICYCLOPENTENYLOXYETHYL METHACRYLATE COPOLYMER; COALESCING, CROSSLINKING; PAINTS, LACQUERS | ELF ATOCHEM S.A. (FR) | 1998-10-20 | — | — | US | claimed |
| EP-0740691-B1 | PHOTOCURABLE FILM-FORMING ACRYLIC LATICES | ATOCHEM ELF SA (FR) | 1998-07-15 | — | — | EP | claimed |
| US-5623001-A | ULTRAVIOLET CURABLE INK JET PRINTING | SCITEX CORPORATION LTD. (IL) | 1997-04-22 | — | — | US | claimed |
| EP-0196324-A4 | POST-TREATMENT OF CURED, RADIATION SENSITIVE POLYMERIZABLE RESINS. | MACDERMID INC (US) | 1988-01-21 | — | — | EP | claimed |
| EP-0196324-A1 | POST-TREATMENT OF CURED, RADIATION SENSITIVE POLYMERIZABLE RESINS | MACDERMID, INCORPORATED (US) | 1986-10-08 | — | — | EP | claimed |
| US-4603058-A | IMMERSION IN ETHYLENICALLY UNSATURATED MONOMER, EXPOSURE TO ACTINIC RADIATION | MACDERMID, INCORPORATED (US) | 1986-07-29 | — | — | US | claimed |
| WO-1986002177-A1 | POST-TREATMENT OF CURED, RADIATION SENSITIVE POLYMERIZABLE RESINS | MACDERMID, INCORPORATED (US) | 1986-04-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050214479-A1 | Compound for optical materials and methods of fabrication | AFF2, AFF1, ELOVL6 | ALDH1A1 2964/4885TDP1 4421/4885KDM4E 3041/4885 |
| US-12597639-B2 | Solid polymer electrolyte for batteries | LEF1, FOS, PUF60 | ALDH1A1 4265/4885TDP1 2106/4885KDM4E 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.