Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ATF4 | P18848 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872199 | 0.95 | PTGS2 (0.74) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL23605967 | 0.90 | PTGS2 (0.68) | PTGS2L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL2116437 | 0.90 | PTGS2 (0.66) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL24805907 | 0.85 | PTGS2 (0.62) | PTGS2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL17365269 | 0.84 | PTGS2 (0.60) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL12061812 | 0.84 | GAA (0.66) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL3913180 | 0.84 | PTGS2 (0.60) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL11151346 | 0.83 | PTGS2 (0.59) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL13935133 | 0.82 | PTGS2 (0.58) | PTGS2L3MBTL1ALDH1A1CYP2C19MEN1 | |
| SCHEMBL7068289 | 0.82 | LMNA (0.59) | PTGS2L3MBTL1CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101391969-B | Method for preparing N-methyl-2-(2,4-dichlorophenoxy) acetamide | SHANGHAI INST TECHNOLOGY | 2012-05-09 | — | — | CN | claimed |
| CN-101391968-A | N-ethyl-2-(4-chlorophenoxy) acetamide and preparation method thereof | SHANGHAI INST TECHNOLOGY (CN) | 2009-03-25 | — | — | CN | claimed |
| CN-101391969-A | Method for preparing N-methyl-2-(2,4-dichlorophenoxy) acetamide | SHANGHAI INST TECHNOLOGY (CN) | 2009-03-25 | — | — | CN | claimed |
| US-4145432-A | 6-ACYLORYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND A METHOD OF EFFECTING VASODILATION THEREWITH | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | claimed |
| US-20240327323-A1 | Methods of Treating of Halogen- Containing Waste Plastic to Produce Halogenated Products | U. S. DEPARTMENT OF ENERGY | 2024-10-03 | — | — | US | disclosed |
| CN-111201245-B | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117736082-A | Preparation method of phenoxy carboxylic acid herbicide | 山东润博生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117645540-A | Preparation method of chlorophenoxycarboxylate | 山东润博生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117466730-A | Preparation method of phenoxy carboxylate herbicide | 山东润博生物科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115260049-B | Method for preparing 2-chloro-N-methylacetanilide by taking wheat straw lignin as raw material | 宿州学院 | 2023-11-07 | — | — | CN | disclosed |
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
| US-7169794-B2 | 6-substituted pyrido-pyrimidines | ROCHE PALO ALTO LLC (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1361880-B1 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | EP | disclosed |
| US-20040116698-A1 | 6-Substituted pyrido-pyrimidines | CHEN JIAN JEFFREY (US) | 2004-06-17 | — | — | US | disclosed |
| US-6696566-B2 | SELECTIVE P38 KINASE INHIBITORS RELATIVE TO CYCLIN-DEPENDENT KINASES AND TYROSINE KINASES | SYNTEX (U.S.A.) LLC | 2004-02-24 | — | — | US | disclosed |
| EP-1361880-A2 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-20030171584-A1 | Treating p38 mediated disorders such as arthritis, Crohns disease, irritable bowel syndrome adult respiratory distress syndrome or chronic obstructive pulmonary disease. | SYNTEX (U.S.A.) LLC | 2003-09-11 | — | — | US | disclosed |
| WO-2002064594-A2 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-22 | — | — | WO | disclosed |
| US-5185341-A | Antiamnestic, antihypoxic compounds | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1993-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327323-A1 | Methods of Treating of Halogen- Containing Waste Plastic to Produce Halogenated Products | VCL, SLC6A12, TPO | PTGS2 4104/4885L3MBTL1 1845/4885ALDH1A1 1975/4885 |
| US-20230165848-A1 | CHEMICAL COMPOUNDS | ATF4, XBP1, EIF2B5 | PTGS2 1508/4885L3MBTL1 260/4885ALDH1A1 3046/4885 |
| US-20030171584-A1 | Treating p38 mediated disorders such as arthritis, Crohns disease, irritable bowel syndrome adult respiratory distress syndrome or chronic obstructive pulmonary disease. | ARRB1, MAPK1, MAPK8 | PTGS2 391/4885L3MBTL1 3254/4885ALDH1A1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.