Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514095 | 0.78 | HRH3 (0.35) | PLATHRH3HTR2AHTR2CHTR2B | |
| SCHEMBL514361 | 0.69 | GRM5 (0.41) | GPR119 | |
| SCHEMBL4371882 | 0.68 | — | — | |
| SCHEMBL512905 | 0.68 | RAB9A (0.51) | MAOBPLATHTR2C | |
| SCHEMBL8056839 | 0.67 | GPR119 (0.35) | MAOAMAOBGPR119 | |
| SCHEMBL1673933 | 0.67 | NR1H4 (0.47) | MAOAMAOBPLATGPR119 | |
| Hydrochloric Acid SCHEMBL514637 | 0.66 | NR1H4 (0.46) | MAOAMAOBPLATGPR119 | |
| SCHEMBL512779 | 0.64 | MAOA (0.44) | MAOAMAOB | |
| SCHEMBL12505995 | 0.63 | GPR119 (0.62) | MAOAMAOBPLATGPR119 | |
| SCHEMBL12069932 | 0.62 | MAOA (0.35) | MAOAMAOBPLATGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | MAOA 412/4885MAOB 309/4885PLAT 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.