Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | UTRN | P46939 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513254 | 0.86 | TP53 (0.45) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL513092 | 0.85 | NPC1 (0.46) | RAB9ANPC1ALDH1A1KDM4EGAA | |
| SCHEMBL513589 | 0.84 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL513204 | 0.83 | HDAC6 (0.44) | RAB9ANPC1NR1H4ALDH1A1KDM4E | |
| SCHEMBL513366 | 0.82 | RAB9A (0.52) | RAB9ANPC1NPSR1ALDH1A1KDM4E | |
| SCHEMBL513221 | 0.78 | CHRNB2 (0.49) | RAB9ANPC1NPSR1ALDH1A1KDM4E | |
| SCHEMBL77275 | 0.78 | RAB9A (0.60) | RAB9ANPC1NPSR1NR1H4ALDH1A1 | |
| SCHEMBL513425 | 0.77 | NPC1 (0.45) | RAB9ANPC1NPSR1ALDH1A1GAA | |
| SCHEMBL512093 | 0.75 | NPC1 (0.41) | RAB9ANPC1ALDH1A1KDM4EGAA | |
| SCHEMBL29024551 | 0.74 | PGK1 (0.53) | NPSR1ALDH1A1HDAC1PTPN5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | RAB9A 2058/4885NPC1 4017/4885NPSR1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.