Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.37 |
| ▸ | ATP4B | P51164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039695 | 0.77 | AKT1 (0.35) | — | |
| SCHEMBL2959502 | 0.67 | SIGMAR1 (0.41) | CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11708552 | 0.65 | PTGS1 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9386634 | 0.65 | HSD11B1 (0.34) | CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4963101 | 0.60 | DHODH (0.34) | — | |
| SCHEMBL8611285 | 0.59 | OPRM1 (0.40) | — | |
| SCHEMBL5032825 | 0.57 | CYP19A1 (0.50) | ATP4AATP4B | |
| SCHEMBL4591277 | 0.57 | ATP4A (0.36) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4985180 | 0.57 | ATP4A (0.36) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5989299 | 0.57 | ATP4A (0.36) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984969-B1 | FUSED DIHYDROPYRANS | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-6160119-A | Fused dihydropyrans | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-12 | — | — | US | disclosed |