Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134144 | 0.94 | DRD2 (0.33) | SIGMAR1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL5586065 | 0.89 | SIGMAR1 (0.33) | SIGMAR1LTA4H | |
| SCHEMBL5586038 | 0.86 | BDKRB2 (0.31) | — | |
| SCHEMBL5585804 | 0.82 | DRD2 (0.35) | SIGMAR1MEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL5585752 | 0.80 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL5585662 | 0.78 | SIGMAR1 (0.31) | SIGMAR1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL25200973 | 0.77 | — | — | |
| SCHEMBL5585632 | 0.75 | OPRM1 (0.30) | — | |
| SCHEMBL19336780 | 0.75 | GNAI3 (0.34) | ALOX5SIGMAR1NPC1HTTRAB9A | |
| SCHEMBL5586029 | 0.74 | DRD2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004744-A1 | COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120797-A1 | COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |