Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484463 | 0.76 | IDO1 (0.41) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL29768740 | 0.76 | IDO1 (0.43) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL1999868 | 0.76 | IDO1 (0.43) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL30057873 | 0.74 | CES2 (0.52) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL1902230 | 0.74 | CES2 (0.52) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL3454906 | 0.73 | IDO1 (0.42) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL4837075 | 0.73 | IDO1 (0.38) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL29244266 | 0.73 | IDO1 (0.42) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL27668701 | 0.73 | MEN1 (0.49) | IDO1TDO2CES2CES1CYP3A4 | |
| SCHEMBL2066940 | 0.73 | IDO1 (0.45) | IDO1TDO2CES2CES1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183075-C | Benzene derivative and its prepn. method | �����ɷ� | 2005-01-05 | — | — | CN | claimed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | claimed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | claimed |
| JP-10017544-A | — | — | None | — | — | JP | disclosed |
| CN-110240587-B | Aryl difluoro benzyl ether compounds, preparation method and application | 中国科学院上海药物研究所 | 2022-01-04 | — | — | CN | disclosed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | disclosed |
| CN-101360513-A | Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof | KOREA INST SCI & TECH (KR) | 2009-02-04 | — | — | CN | disclosed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-20060177603-A1 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2006-08-10 | — | — | US | disclosed |
| CN-1183075-C | Benzene derivative and its prepn. method | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| CN-1183075-C | Benzene derivative and its prepn. method | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| JP-2003261478-A | METHOD FOR PRODUCING DIFLUOROBENZYL BROMIDE DERIVATIVE AND DIFLUOROBENZYL ETHER DERIVATIVE | SEIMI CHEM CO LTD | 2003-09-16 | — | — | JP | disclosed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| US-6231785-B1 | USEFUL FOR LIQUID CRYSTALLINE MATERIALS | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | disclosed |
| CN-1255475-A | Benzene derivative and its prepn. method | CHISSO CORP (JP) | 2000-06-07 | — | — | CN | disclosed |
| JP-2000095715-A | BENZENE DERIVATIVE AND ITS PRODUCTION | CHISSO CORP | 2000-04-04 | — | — | JP | disclosed |
| JP-H1017544-A | THION-O-ESTER DERIVATIVE AND ITS PRODUCTION | CHISSO CORP | 1998-01-20 | — | — | JP | disclosed |
| US-5651919-A | Benzyl ether derivative and composition containing the same | CITIZEN WATCH CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | IDO1 1990/4885TDO2 882/4885CES2 583/4885 |
| US-20060177603-A1 | Benzochromene derivatives | SBDS, CCND2, DDT | IDO1 1693/4885TDO2 194/4885CES2 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.