Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084801 | 0.77 | ALDH1A1 (0.35) | GRIA4GRIA2KCNH2HTR7CA2 | |
| SCHEMBL2085965 | 0.65 | HTR7 (0.35) | HTR7CA2CA9CA12 | |
| SCHEMBL11689429 | 0.60 | TSHR (0.48) | CA1CA2CA9CA12 | |
| SCHEMBL13651816 | 0.60 | ALDH1A1 (0.40) | KCNH2CA2CA9CA12 | |
| SCHEMBL803901 | 0.59 | PTGS2 (0.68) | PTGS2CA1CA2CA9CA12 | |
| SCHEMBL28935583 | 0.59 | MAOA (0.39) | KCNH2CA2CA9CA12 | |
| SCHEMBL8950639 | 0.59 | GABRP (0.71) | — | |
| SCHEMBL1225841 | 0.58 | TSHR (0.50) | CA2CA9CA12 | |
| SCHEMBL1226208 | 0.58 | TSHR (0.50) | CA2CA9CA12 | |
| SCHEMBL1225840 | 0.58 | TSHR (0.50) | CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611120-A4 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CORTICAL PTY LTD (AU) | 2008-04-23 | — | — | EP | disclosed |
| EP-1611120-A1 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Cortical Pty Ltd (AU) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089927-A1 | NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CORTICAL PTY LTD (AU) | 2004-10-21 | — | — | WO | disclosed |