SCHEMBL514173

SCHEMBL514173

[CH2]S(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
LMNA P02545 2/20 0.62
HTR6 P50406 2/20 0.62
MPO P05164 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CA2 P00918 5/20 0.59
CA9 Q16790 5/20 0.59
CA1 P00915 4/20 0.59
CA12 O43570 4/20 0.59
CA14 Q9ULX7 2/20 0.59
AGO2 Q9UKV8 2/20 0.59
CA4 P22748 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
USP2 O75604 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA13 Q8N1Q1 1/20 0.59
CA5B Q9Y2D0 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dapsone SCHEMBL21428 0.77 HTR6 (1.00) TSHRLMNAHTR6MPOCYP3A4
Dapsone SCHEMBL5055312 0.77 HTR6 (1.00) TSHRLMNAHTR6MPOCYP3A4
SCHEMBL10596934 0.77 HTR6 (1.00) TSHRLMNAHTR6MPOCYP3A4
SCHEMBL324893 0.77 HTR6 (1.00) TSHRLMNAHTR6MPOCYP3A4
Dapsone SCHEMBL1219599 0.77 HTR6 (1.00) TSHRLMNAHTR6MPOCYP3A4
Sulfanilamide SCHEMBL2746422 0.76 CA2 (0.90) TSHRLMNAHTR6MPOCYP3A4
Sulfanilamide SCHEMBL11751516 0.76 CA2 (0.90) TSHRLMNAHTR6MPOCYP3A4
Dapsone SCHEMBL9690514 0.74 HTR6 (0.94) TSHRLMNAHTR6MPOCYP3A4
Sulfanilamide SCHEMBL2798899 0.74 CA2 (1.00) TSHRLMNAHTR6MPOCYP3A4
Dapsone SCHEMBL2203636 0.74 HTR6 (0.94) TSHRLMNAHTR6MPOCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
CN-115916966-A STRAD binding agents and uses thereof 加利福尼亚大学董事会 2023-04-04 CN disclosed
US-11460767-B2 Composition for film formation, film-forming method and directed self-assembly lithography process JSR CORPORATION (JP) 2022-10-04 US disclosed
US-20190233561-A1 COMPOSITION FOR FILM FORMATION, FILM-FORMING METHOD AND DIRECTED SELF-ASSEMBLY LITHOGRAPHY PROCESS JSR CORPORATION (JP) 2019-08-01 US disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 TSHR 307/4885LMNA 4076/4885HTR6 3396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.