SCHEMBL514279

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL515055	0.78	KMT2A (0.50)	CYP3A4IDO1CYP1A2TDP1CA1
	SCHEMBL514597	0.78	RECQL (0.48)	RCE1CYP3A4TDP1CA1CA2
	SCHEMBL4503685	0.78	CA2 (0.52)	RCE1CA2ALDH1A1HPGD
	SCHEMBL16503565	0.77	PTGS2 (0.47)	CYP3A4IDO1APPCYP1A2CYP2D6
	SCHEMBL1678837	0.76	L3MBTL1 (0.50)	CYP3A4IDO1KDM4EALDH1A1
	SCHEMBL4949390	0.76	ENPP2 (0.50)	CA2
	SCHEMBL710399	0.76	CA1 (0.50)	RCE1NPC1TDP1CA1CA2
	SCHEMBL777188	0.76	KMT2A (0.44)	IDO1LMNA
	SCHEMBL18517162	0.76	ALDH1A1 (0.40)	RCE1NPC1TDP1CA1CA2
	SCHEMBL3126969	0.76	CA1 (0.40)	CYP3A4IDO1APPCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.