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SCHEMBL5144091

SCHEMBL5144091

C/C(=C\[Si](c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 1/20 0.50
▸ MAPT P10636 2/20 0.46
▸ CES2 O00748 1/20 0.40
▸ CES1 P23141 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ APEX1 P27695 8/20 0.39
▸ RXRA P19793 1/20 0.38
▸ RXRB P28702 1/20 0.38
▸ NR4A2 P43354 1/20 0.38
▸ RXRG P48443 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ GLA P06280 2/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3297070 1.00 AKR1C3 (0.50) AKR1C3MAPTCES2CES1CYP2C9
SCHEMBL5907875 0.86 LMNA (0.39) AKR1C3MAPTALDH1A1
SCHEMBL3297649 0.84 ALDH1A1 (0.39) AKR1C3MAPTCES2CES1HTT
SCHEMBL3787971 0.82 MAPT (0.49) AKR1C3MAPTCES2CES1CYP2C9
SCHEMBL3293184 0.82 MAPT (0.49) AKR1C3MAPTCES2CES1CYP2C9
SCHEMBL5907882 0.80 NR4A1 (0.47) AKR1C3CES2CES1RXRARXRB
SCHEMBL5907699 0.78 CES2 (0.36) AKR1C3CES2CES1APEX1NPC1
SCHEMBL560335 0.77 AKR1C3 (0.44) AKR1C3MAPTCES2CES1CYP2C9
SCHEMBL17420014 0.77 AKR1C3 (0.44) AKR1C3MAPTCES2CES1CYP2C9
SCHEMBL4917439 0.77 AKR1C3 (0.44) AKR1C3MAPTCES2CES1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001345-B1 DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF UNIV SOUTH CHINA TECH (CN) 2026-04-01 — — EP claimed
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 — — US claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 — — EP claimed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 — — EP claimed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 — — US claimed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 — — US claimed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 — — EP claimed
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 — — US disclosed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 — — EP disclosed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 — — EP disclosed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 — — US disclosed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 — — US disclosed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 — — EP disclosed