SCHEMBL5144290

SCHEMBL5144290

CC(C(=O)O)C(=O)OC(C)(C)CCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
PRSS1 P07477 1/20 0.39
CTSG P08311 1/20 0.39
CTRB1 P17538 1/20 0.39
CMA1 P23946 1/20 0.39
TSHR P16473 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
KIF11 P52732 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504292 0.88 NAAA (0.44) NAAATDP1TSHRKMT2ASMN1; SMN2
SCHEMBL31506757 0.79 NAAA (0.41) NAAATDP1
SCHEMBL873380 0.79 ALDH1A1 (0.48) NAAATDP1KMT2AMEN1SMN1; SMN2
SCHEMBL4630907 0.78 MEN1 (0.52) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL5145960 0.78 NPC1 (0.45) NAAATDP1ALDH1A1CYP2C9CYP2C19
SCHEMBL26697028 0.78 LMNA (0.49) NAAATDP1KMT2AMEN1KIF11
SCHEMBL16672886 0.76 CYP1A2 (0.48) TDP1PRSS1CTSGCTRB1CMA1
SCHEMBL16673187 0.75 KMT2A (0.41) NAAATDP1TSHRKMT2ASMN1; SMN2
SCHEMBL5145964 0.75 NPC1 (0.43) NAAATDP1SMN1; SMN2ALDH1A1CYP2C19
SCHEMBL5146853 0.74 PPARG (0.38) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240552-B1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS INTELLECTUAL VENTURES HOLDING 40 LLC (US) 2012-09-19 EP disclosed
EP-1240552-A4 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS UNIV TEXAS (US) 2007-10-17 EP disclosed
EP-1240552-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS Board of Regents, The University of Texas System (US) 2002-09-18 EP disclosed
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed
US-6369110-B1 PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM SUMITOMO PHARMACEUTICALS COMPANY (JP) 2002-04-09 US disclosed
WO-2001013179-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 2001-02-22 WO disclosed