Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 11/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ACLY | P53396 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273182 | 0.93 | PTGS2 (0.66) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL2271243 | 0.90 | ADCY1 (0.61) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL1066393 | 0.87 | HDAC1 (0.65) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL2272541 | 0.86 | PTGS2 (0.63) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL2277756 | 0.85 | PTGS2 (0.57) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL2276607 | 0.84 | CASP3 (0.63) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL1317635 | 0.83 | ACLY (0.53) | NPC1SMN1; SMN2ACLYKMT2AMEN1 | |
| SCHEMBL2274216 | 0.83 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL2270222 | 0.83 | DHODH (0.77) | NPC1RAB9APKMACLYKMT2A | |
| SCHEMBL2274795 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |