SCHEMBL5146018

SCHEMBL5146018

C=[C]C(COc1ccccc1)C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
HIF1A Q16665 1/20 0.40
IDO1 P14902 2/20 0.38
KDM4E B2RXH2 1/20 0.38
SCN4A P35499 2/20 0.38
NPC1 O15118 1/20 0.38
PKM P14618 1/20 0.38
EPHX2 P34913 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
METAP2 P50579 2/20 0.37
METAP1 P53582 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809168 0.76 LMNA (0.50) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL3089313 0.73 LMNA (0.39) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL4066072 0.71 LMNA (0.41) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL6727689 0.70 SCN4A (0.55) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL6727693 0.70 SCN4A (0.55) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL6727697 0.70 SCN4A (0.55) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL7430414 0.67 SCN4A (0.39) LMNAMEN1KMT2ACYP2D6TSHR
SCHEMBL14118821 0.67 KDM4E (0.46) IDO1KDM4ENPC1PKMEPHX2
SCHEMBL1356987 0.66 METAP2 (0.45) MEN1KMT2ATSHRIDO1NPC1
SCHEMBL61120 0.66 IDO1 (0.44) LMNAIDO1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070128547-A1 POSITIVE RESIST COMPOSITION FUJI PHOTO FILM CO., LTD. 2007-06-07 US disclosed