Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 4/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144717 | 0.87 | NAAA (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL4838617 | 0.82 | PKM (0.57) | PKMMEN1KMT2APRMT5WDR77 | |
| SCHEMBL3746577 | 0.82 | PKM (0.57) | PKMMEN1KMT2APRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL28750033 | 0.81 | PKM (0.55) | PKMMEN1KMT2APRMT5WDR77 | |
| SCHEMBL9328613 | 0.81 | ESR1 (0.42) | PKMMEN1KMT2ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL4196019 | 0.81 | PKM (0.55) | PKMMEN1KMT2APRMT5WDR77 | |
| SCHEMBL27874655 | 0.80 | FFAR2 (0.36) | TSHRSMN1; SMN2RORARORCGLS | |
| SCHEMBL996521 | 0.79 | TSHR (0.54) | TSHRMEN1KMT2ASMN1; SMN2MALT1 | |
| SCHEMBL27577102 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL3535148 | 0.75 | BRD4 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259907-A1 | ARYL AND ARYLALKYLENYL SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259907-A1 | ARYL AND ARYLALKYLENYL SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | IL2, TSLP, IFNG | PKM 2767/4885TSHR 240/4885MEN1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.