SCHEMBL4521937

SCHEMBL4521937

C1=CC(N(c2ccccc2)c2c3ccccc3cc3ccccc23)(N(c2ccccc2)c2c3ccccc3cc3ccccc23)C=CC1c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5148248 0.82 ALDH1A1 (0.35) ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL8209205 0.80
SCHEMBL419796 0.80 SIGMAR1 (0.38) KDM4EALDH1A1CYP1A2CYP2C19
SCHEMBL2802019 0.78 KDM1A (0.31) KDM4ECYP1A2CYP2C19
SCHEMBL8209184 0.78 CYP1A2 (0.32) ALDH1A1CYP1A2HPGDHSD17B10
SCHEMBL8211332 0.76 CYP1A2 (0.32) MEN1ALDH1A1CYP1A2HPGDKMT2A
SCHEMBL16331595 0.76 CA12 (0.36) CYP1A2CYP2C19
SCHEMBL6711335 0.75 PKM (0.30)
SCHEMBL9190411 0.74 TSPO (0.31)
SCHEMBL9192026 0.74 MEN1 (0.32) MEN1ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10461269-B2 Crosslinkable, /polymerizable and combinations thereof charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof for organic light emitting diodes and other organic electronics and photonics applications and method of making same MOLECULAR GLASSES, INC. (US) 2019-10-29 US disclosed
US-8207914-B2 OLED display with aging compensation GLOBAL OLED TECHNOLOGY LLC (US) 2012-06-26 US disclosed
US-20090162644-A1 ORGANIC ELEMENT FOR LOW VOLTAGE ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC 2009-06-25 US disclosed
US-20070103411-A1 OLED display with aging compensation EASTMAN KODAK COMPANY 2007-05-10 US disclosed