Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28882618 | 0.87 | TSHR (0.80) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| SCHEMBL3719208 | 0.85 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| Butane SCHEMBL2906063 | 0.85 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| Alcohol SCHEMBL281881 | 0.85 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| SCHEMBL27464245 | 0.85 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| (Phenylsulfonyl)Benzene SCHEMBL1679634 | 0.83 | HTR6 (0.64) | TSHRSMN1; SMN2PSIP1POLBHSD11B1 | |
| Ethylamine SCHEMBL5875345 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| SCHEMBL29118883 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| Alcohol SCHEMBL28562710 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 | |
| Alcohol SCHEMBL28250646 | 0.83 | TSHR (0.73) | TSHRSMN1; SMN2PSIP1POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113881418-B | Alkylaniline polyether benzene sulfonate oil displacement surfactant and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-115500232-A | Cultivation method for improving ornamental quality of begonia aquifolium | 云南省农业科学院花卉研究所 | 2022-12-23 | — | — | CN | claimed |
| CN-102199161-B | Benzene sulfonic acid clopidogrel with crystal form I, preparation method thereof and application thereof | TIANJIN CHASESUN PHARM CO LTD | 2013-07-03 | — | — | CN | claimed |
| CN-102199161-A | Benzene sulfonic acid clopidogrel with crystal form I, preparation method thereof and application thereof | TIANJIAN CHASESUN PHARMACEUTICAL CO LTD | 2011-09-28 | — | — | CN | claimed |
| CN-115500232-A | Cultivation method for improving ornamental quality of begonia aquifolium | 云南省农业科学院花卉研究所 | 2022-12-23 | — | — | CN | disclosed |
| CN-111869672-B | Bactericidal composition and application thereof | 河北省农林科学院植物保护研究所 | 2021-06-22 | — | — | CN | disclosed |
| CN-108477199-B | Bactericidal composition and application thereof | 河北省农林科学院植物保护研究所 | 2021-01-22 | — | — | CN | disclosed |
| CN-111869672-A | Bactericidal composition and application thereof | 河北省农林科学院植物保护研究所 | 2020-11-03 | — | — | CN | disclosed |
| CN-102199161-B | Benzene sulfonic acid clopidogrel with crystal form I, preparation method thereof and application thereof | TIANJIN CHASESUN PHARM CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-102285996-A | Benzenesulfonic acid clopidogrel crystal form II, preparation method and application thereof | — | 2011-12-21 | — | — | CN | disclosed |
| CN-102199161-A | Benzene sulfonic acid clopidogrel with crystal form I, preparation method thereof and application thereof | TIANJIAN CHASESUN PHARMACEUTICAL CO LTD | 2011-09-28 | — | — | CN | disclosed |
| EP-1539707-A4 | METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION | BIODIEM LTD (AU) | 2007-05-30 | — | — | EP | disclosed |
| US-20060135587-A1 | Method and compounds for promoting healing and reducing inflammation | BIODIEM, LTD. (AU) | 2006-06-22 | — | — | US | disclosed |
| EP-1539707-A1 | METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION | Biodiem Ltd. (AU) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004013108-A1 | METHOD AND COMPOUNDS FOR PROMOTING HEALING AND REDUCING INFLAMMATION | BIODIEM LIMITED (AU) | 2004-02-12 | — | — | WO | disclosed |
| EP-1049659-A1 | FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME | AlliedSignal Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| US-6133472-A | OXYVINYL GROUPS SEPARATED FROM FLUORINE CONTAINING GROUPS BY AT LEAST ONE ALKYLENE GROUP HAVING 2-8 CARBON ATOMS AND BY AT LEAST ONE OXYGEN ATOM IN ADDITION TO THE OXYGEN ON THE OXYVINYL; READILY RADIATION CURABLE | ALLIEDSIGNAL INC. (US) | 2000-10-17 | — | — | US | disclosed |
| WO-1999036381-A1 | FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME | ALLIEDSIGNAL INC. (US) | 1999-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135587-A1 | Method and compounds for promoting healing and reducing inflammation | IL1B, MIF, ALKBH5 | TSHR 4776/4885SMN1; SMN2 2994/4885PSIP1 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.