Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803641 | 0.85 | STAT3 (0.51) | STAT3STAT1TERT | |
| Hydrochloric Acid SCHEMBL5150597 | 0.84 | STAT3 (0.32) | STAT3STAT1KDM4E | |
| SCHEMBL3617508 | 0.83 | TERT (0.40) | TERTKDM4E | |
| SCHEMBL6007193 | 0.81 | STAT3 (0.49) | STAT3STAT1TERT | |
| SCHEMBL5139610 | 0.79 | STAT3 (0.54) | STAT3STAT1TERT | |
| SCHEMBL473158 | 0.72 | STAT3 (0.86) | STAT3STAT1TERT | |
| SCHEMBL30753635 | 0.72 | STAT3 (0.86) | STAT3STAT1TERT | |
| SCHEMBL6007192 | 0.72 | STAT3 (0.36) | STAT3STAT1TERT | |
| SCHEMBL460724 | 0.71 | STAT3 (0.59) | STAT3STAT1KDM4E | |
| SCHEMBL1275381 | 0.71 | STAT3 (0.84) | STAT3STAT1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207582-A1 | Substituted Porphyrins | DUKE UNIVERSITY (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207582-A1 | Substituted Porphyrins | SOD3, MPO, SOD1 | STAT3 1497/4885STAT1 1104/4885TERT 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.