Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803641 | 0.85 | STAT3 (0.51) | STAT3STAT1TERT | |
| SCHEMBL450416 | 0.81 | TERT (0.54) | TERT | |
| SCHEMBL5139609 | 0.81 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL29469529 | 0.81 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL6007193 | 0.81 | STAT3 (0.49) | STAT3STAT1TERT | |
| SCHEMBL17668308 | 0.80 | TERT (0.53) | TERT | |
| Hydrochloric Acid SCHEMBL2555721 | 0.80 | TERT (0.53) | TERT | |
| Hydrochloric Acid SCHEMBL5150601 | 0.79 | STAT3 (0.47) | STAT3STAT1TERT | |
| Hydrochloric Acid SCHEMBL2553046 | 0.79 | TERT (0.52) | TERT | |
| Hydrochloric Acid SCHEMBL2555716 | 0.79 | TERT (0.52) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207582-A1 | Substituted Porphyrins | DUKE UNIVERSITY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070179124-A1 | Substituted Porphyrins | FRIDOVICH IRWIN | 2007-08-02 | — | — | US | disclosed |
| US-20060074062-A1 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2006-04-06 | — | — | US | disclosed |
| US-6916799-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1045851-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2003-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179124-A1 | Substituted Porphyrins | PPOX, GPX4, PRDX5 | STAT3 892/4885STAT1 1589/4885TERT 821/4885 |
| US-20080207582-A1 | Substituted Porphyrins | SOD3, MPO, SOD1 | STAT3 1497/4885STAT1 1104/4885TERT 1398/4885 |
| US-20060074062-A1 | Substituted porphyrins | PPOX, GPX4, PRDX5 | STAT3 892/4885STAT1 1589/4885TERT 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.