Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154475 | 0.88 | KMT2A (0.54) | KMT2AMEN1LMNAALDH1A1RAB9A | |
| SCHEMBL15183798 | 0.85 | MEN1 (0.62) | RXRARXRBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18311606 | 0.84 | LMNA (0.59) | RXRARXRBSMN1; SMN2LMNANPC1 | |
| SCHEMBL9149730 | 0.83 | L3MBTL1 (0.63) | KMT2ASMN1; SMN2MEN1LMNANPC1 | |
| SCHEMBL8479394 | 0.82 | HPGD (0.64) | KMT2ASMN1; SMN2MEN1LMNANPC1 | |
| SCHEMBL307233 | 0.82 | KMT2A (0.75) | KMT2ASMN1; SMN2MEN1LMNANPC1 | |
| SCHEMBL2586835 | 0.81 | KMO (0.59) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL23289051 | 0.81 | HPGD (0.62) | KMT2ASMN1; SMN2MEN1LMNANPC1 | |
| SCHEMBL30913837 | 0.81 | HPGD (0.62) | KMT2ASMN1; SMN2MEN1LMNANPC1 | |
| SCHEMBL16994145 | 0.80 | RAB9A (0.56) | KMT2ASMN1; SMN2MEN1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060573-A1 | Acyltryptophanols | FSHR, NPY1R, NPY2R | RXRA 1256/4885RXRB 1669/4885KMT2A 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.