SCHEMBL5515030

SCHEMBL5515030

COc1c(C(=O)O)c[nH]c1NCC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
GSK3B P49841 1/20 0.32
PTGS2 P35354 1/20 0.32
CDK2 P24941 1/20 0.32
APEX1 P27695 3/20 0.32
PRKAB2 O43741 2/20 0.32
PRKAG1 P54619 2/20 0.32
PRKAA2 P54646 2/20 0.32
PRKAA1 Q13131 2/20 0.32
PRKAG3 Q9UGI9 2/20 0.32
PRKAG2 Q9UGJ0 2/20 0.32
PRKAB1 Q9Y478 2/20 0.32
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.31
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13698067 0.71 HSD17B10 (0.42) KDM4EHSD17B10MAPTTDP1ALDH1A1
SCHEMBL5153802 0.71 PKM (0.44) KDM4EHSD17B10MAPTTDP1ALDH1A1
Butane SCHEMBL4112579 0.69 HSD17B10 (0.38) KDM4EHSD17B10MAPTTDP1ALDH1A1
SCHEMBL755293 0.67 KDM4E (0.48) KDM4EHSD17B10MAPTTDP1ALDH1A1
SCHEMBL5512441 0.67 ASPH (0.46) KDM4EMAPTTDP1ALDH1A1PTGS2
SCHEMBL30819290 0.65 KDM4E (0.46) KDM4EHSD17B10MAPTTDP1ALDH1A1
SCHEMBL6206909 0.64 KDM4E (0.41) KDM4EHSD17B10MAPTTDP1ALDH1A1
Hydrochloric Acid SCHEMBL2202243 0.63 TDP1 (0.59) KDM4EHSD17B10MAPTTDP1ALDH1A1
SCHEMBL13475490 0.62 MEN1 (0.56) KDM4EMAPTALDH1A1HPGDCDK2
SCHEMBL1505827 0.61 TDP1 (0.61) KDM4EHSD17B10MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed