SCHEMBL5154510

SCHEMBL5154510

O=C(c1ccc(Br)cc1OC(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 7/20 0.37
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
DGAT1 O75907 1/20 0.37
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5236256 0.82 KDM4E (0.44) MEN1PKMKMT2ADGAT1ALDH1A1
SCHEMBL29333898 0.81 DGAT1 (0.42) MEN1PKMKMT2ADGAT1ALDH1A1
SCHEMBL15105948 0.81 PTGDR2 (0.45) MEN1PKMKMT2ADGAT1MAOA
SCHEMBL5236111 0.78 KMT2A (0.46) MEN1PKMKMT2AALDH1A1
SCHEMBL15106217 0.78 GSK3B (0.41) MEN1PKMKMT2ADGAT1ALDH1A1
SCHEMBL22979540 0.77 OGG1 (0.42) MEN1PKMKMT2ADGAT1ALDH1A1
SCHEMBL28176626 0.77 ALDH1A1 (0.41) MEN1PKMKMT2AALDH1A1
SCHEMBL8745851 0.74 SLC6A4 (0.44) KMT2AALDH1A1
SCHEMBL392086 0.73 KDM4E (0.50) MEN1KMT2AALDH1A1
SCHEMBL29395694 0.73 DGAT1 (0.61) IDO1MEN1KMT2ADGAT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
EP-1671941-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 IDO1 488/4885MEN1 4633/4885PKM 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.