SCHEMBL5154730

SCHEMBL5154730

Cc1cc(C)c(-[n+]2ccc(-c3cc[n+](C)cc3)cc2)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SLC6A4 P31645 2/20 0.45
▸ SLC22A2 O15244 1/20 0.45
▸ SLC22A1 O15245 1/20 0.45
▸ SLC22A3 O75751 1/20 0.45
▸ QDPR P09417 2/20 0.41
▸ PABPC1 P11940 1/20 0.41
▸ APOBEC3A P31941 1/20 0.41
▸ EIF4H Q15056 1/20 0.41
▸ APOBEC3G Q9HC16 1/20 0.41
▸ HDAC8 Q9BY41 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157157 0.92 RAPGEF4 (0.33) SLC6A4SLC22A2SLC22A1SLC22A3
Hydrochloric Acid SCHEMBL2469452 0.90 RAB9A (0.33) SLC6A4SLC22A2SLC22A1SLC22A3PABPC1
SCHEMBL6454170 0.81 PABPC1 (0.47) QDPRPABPC1APOBEC3AEIF4HAPOBEC3G
Hydrochloric Acid SCHEMBL193608 0.79 PABPC1 (0.46) QDPRPABPC1APOBEC3AEIF4HAPOBEC3G
SCHEMBL29738939 0.78 SLC22A2 (0.46) SLC6A4SLC22A2SLC22A1SLC22A3QDPR
Paraquat SCHEMBL4895671 0.72 SLC6A4 (0.77) SLC6A4SLC22A2SLC22A1SLC22A3QDPR
Paraquat SCHEMBL21652 0.72 SLC6A4 (0.77) SLC6A4SLC22A2SLC22A1SLC22A3QDPR
Hydrochloric Acid SCHEMBL2462196 0.72 ALDH1A1 (0.65) —
SCHEMBL12598931 0.72 SLC6A4 (0.45) SLC6A4SLC22A2SLC22A1SLC22A3QDPR
SCHEMBL29738922 0.72 SLC6A4 (0.45) SLC6A4SLC22A2SLC22A1SLC22A3QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 — — EP claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 — — EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 — — EP claimed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 — — US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 — — US claimed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 — — EP claimed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 — — WO claimed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 — — EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 — — US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 — — US disclosed
US-6661559-B2 Transparent substrate having an electrically conductive material; redox electroactive compounds; colorimetric analysis GENTEX CORPORATION 2003-12-09 — — US disclosed
US-6288825-B1 Electrochromic media for producing a preselected color and devices comprising same GENTEX CORPORATION 2001-09-11 — — US disclosed
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