Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157543 | 0.81 | KDM4E (0.47) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL5158461 | 0.81 | KMT2A (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5157388 | 0.81 | KDM4E (0.48) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL5155216 | 0.80 | MAOA (0.48) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL5158044 | 0.77 | TUBB4A (0.59) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL5158018 | 0.77 | MAOA (0.43) | HTR7MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5289407 | 0.76 | TUBB4A (0.68) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL5157286 | 0.75 | TUBB4A (0.64) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL5158006 | 0.74 | MAOA (0.48) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL5157758 | 0.74 | TUBB4A (0.63) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746087-A1 | Derivates of 3-indolylmethylene having cytostatic properties | Universitaet Regensburg (DE) | 2007-01-24 | — | — | EP | disclosed |