Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155216 | 0.94 | MAOA (0.48) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5157543 | 0.86 | KDM4E (0.47) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5159722 | 0.83 | MAOA (0.43) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5158461 | 0.83 | KMT2A (0.50) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5158006 | 0.81 | MAOA (0.48) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5157844 | 0.80 | KDM4E (0.51) | MAOAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5157388 | 0.78 | KDM4E (0.48) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL10097344 | 0.78 | MAOA (0.51) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL5154906 | 0.77 | MTNR1A (0.49) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL5158044 | 0.75 | TUBB4A (0.59) | MAOAMAOBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746087-A1 | Derivates of 3-indolylmethylene having cytostatic properties | Universitaet Regensburg (DE) | 2007-01-24 | — | — | EP | disclosed |