Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | GABRE | P78334 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795930 | 0.83 | SLC6A12 (0.36) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9144675 | 0.80 | SLC6A12 (0.37) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29922180 | 0.79 | SLC6A12 (0.36) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7957108 | 0.76 | SMN1; SMN2 (0.57) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8801541 | 0.75 | ALDH1A1 (0.38) | MAPTHTTKLKB1KLK1L3MBTL1 | |
| SCHEMBL5160108 | 0.75 | KEAP1 (0.58) | MAPTKDM4EAKR1C3AKR1C2KEAP1 | |
| SCHEMBL8548280 | 0.75 | SLC6A12 (0.34) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8547431 | 0.74 | HSP90AB1 (0.43) | SLC6A12GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2082345 | 0.73 | TAS1R3 (0.40) | MAPTHTTALDH1A1KDM4ERAB9A | |
| SCHEMBL27446237 | 0.73 | ALDH1A1 (0.37) | MAPTHTTL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |