SCHEMBL5158341

SCHEMBL5158341

O=S(=O)(O[Si](c1cccc2ccccc12)(c1cccc2ccccc12)c1cccc2ccccc12)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
RECQL P46063 1/20 0.35
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 1/20 0.33
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KEAP1 Q14145 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
PGR P06401 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31043061 1.00 CA2 (0.36) CA2CA1CA9RECQLPTGS1
SCHEMBL537935 0.73 CA2 (0.36) CA2CA1CA9PTGS1PTGS2
SCHEMBL29937164 0.71 ALDH1A1 (0.46) CA2CA1CA9PTGS1KDM4E
SCHEMBL1056365 0.71 ALDH1A1 (0.46) CA2CA1CA9PTGS1KDM4E
Hydrogen Sulfide SCHEMBL27507715 0.70 ALDH1A1 (0.45) CA2CA1CA9PTGS1KDM4E
SCHEMBL66198 0.69 CA1 (0.49) CA2CA1CA9KDM4EALDH1A1
SCHEMBL2903663 0.68 CA2 (0.36) CA2CA1CA9RECQLPTGS1
SCHEMBL9745651 0.68 TDP1 (0.45) CA2CYP1A2RORCTDP1MEN1
SCHEMBL718079 0.68 KDM4E (0.38) CA2CA1CA9RECQLKDM4E
SCHEMBL27574998 0.68 CA1 (0.36) CA2CA1CA9RECQLPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428175-B1 METHOD FOR PRODUCING OLIGOSACCHARIDES AND POLYSACCHARIDES HAVING NON-PROTECTED SULFATE GROUPS GLYTECH INC (JP) 2024-09-25 EP claimed
EP-4741410-A1 SOLUBILIZATION GROUP FOR POORLY WATER-SOLUBLE PROTEINS Glytech, Inc. (JP) 2026-05-13 EP disclosed
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH INC (JP) 2024-11-28 US disclosed
US-12103947-B2 Methods for producing peptide thioester and peptide GLYTECH, INC. (JP) 2024-10-01 US disclosed
EP-3428175-B1 METHOD FOR PRODUCING OLIGOSACCHARIDES AND POLYSACCHARIDES HAVING NON-PROTECTED SULFATE GROUPS GLYTECH INC (JP) 2024-09-25 EP disclosed
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE GLYTECH, INC. (JP) 2023-05-11 US disclosed
CN-108884122-B Method for producing sugar having sulfate group and/or phosphate group 株式会社糖锁工学研究所 2022-06-07 CN disclosed
US-10913763-B2 Method for producing sugar having sulfate group and/or phosphate group GLYTECH, INC. (JP) 2021-02-09 US disclosed
US-20200062794-A1 METHOD FOR PRODUCING SUGAR HAVING SULFATE GROUP AND/OR PHOSPHATE GROUP GLYTECH, INC. (JP) 2020-02-27 US disclosed
EP-3428175-A1 METHOD FOR PRODUCING SUGAR HAVING SULFATE GROUP AND/OR PHOSPHATE GROUP Glytech, Inc. (JP) 2019-01-16 EP disclosed
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-09-20 US disclosed
EP-1740620-A1 PREPARATION PROCESS OF OLIGOGLYCOSAMINOGLYCAN, AND REDUCING END GLUCURONIC ACID TYPE OLIGOCHONDROITIN SULFATE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-01-10 EP disclosed
WO-2005092931-A1 PREPARATION PROCESS OF OLIGOGLYCOSAMINOGLYCAN, AND REDUCING END GLUCURONIC ACID TYPE OLIGOCHONDROITIN SULFATE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10913763-B2 Method for producing sugar having sulfate group and/or phosphate group SI, DDOST, PSPH CA2 176/4885CA1 316/4885CA9 134/4885
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same OSTC, B3GAT3, CSGALNACT1 CA2 3117/4885CA1 2259/4885CA9 745/4885
US-20200062794-A1 METHOD FOR PRODUCING SUGAR HAVING SULFATE GROUP AND/OR PHOSPHATE GROUP SI, DDOST, PSPH CA2 176/4885CA1 316/4885CA9 134/4885
US-20230143844-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL CA2 3748/4885CA1 1977/4885CA9 3418/4885
US-12103947-B2 Methods for producing peptide thioester and peptide QPCT, QPCTL, PTMS CA2 3639/4885CA1 1695/4885CA9 3184/4885
US-20240391951-A1 NOVEL METHODS FOR PRODUCING PEPTIDE THIOESTER AND PEPTIDE QPCT, PTMS, QPCTL CA2 3748/4885CA1 1977/4885CA9 3418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.