SCHEMBL537935

SCHEMBL537935

O=S(=O)(O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.36
CA1 P00915 3/20 0.36
CA9 Q16790 2/20 0.36
CA5A P35218 1/20 0.36
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGS1 P23219 3/20 0.33
PTGS2 P35354 3/20 0.33
GPR3 P46089 1/20 0.32
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TSHR P16473 1/20 0.31
HTR6 P50406 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
NR1I2 O75469 1/20 0.30
RORA P35398 1/20 0.30
RORC P51449 1/20 0.30
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196180 0.80 NR1H2 (0.37) CA2CA1CA9CA5AALDH1A1
SCHEMBL196247 0.80 NR1H2 (0.37) CA2CA1CA9CA5AALDH1A1
SCHEMBL17466441 0.78 ELANE (0.37) CA2CA1CA9CA5AALDH1A1
SCHEMBL28382543 0.78 ALDH1A1 (0.39) CA2CA1CA9CA5AALDH1A1
SCHEMBL537975 0.77 CA2 (0.33) CA2CA1CA9CA5APTGS1
SCHEMBL30998871 0.76 PSIP1 (0.34) CA2CA1CA9CA5AHSD17B10
SCHEMBL538583 0.74 KEAP1 (0.37) CA2CA1CA9CA5AALDH1A1
SCHEMBL5158341 0.73 CA2 (0.36) CA2CA1CA9ALDH1A1HSD17B10
SCHEMBL31043061 0.73 CA2 (0.36) CA2CA1CA9ALDH1A1HSD17B10
SCHEMBL2058063 0.72 ALDH1A1 (0.44) CA2CA1CA9CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778615-B1 SILYL PHOSPHINE COMPOUND, METHOD FOR PRODUCING SILYL PHOSPHINE COMPOUND AND METHOD FOR FORMING INP QUANTUM DOT NIPPON CHEMICAL IND (JP) 2024-08-07 EP claimed
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US claimed
US-11578266-B2 Silyl phosphine compound, process for producing silyl phosphine compound and process for producing InP quantum dots NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2023-02-14 US claimed
CN-109715643-B Process for producing silylphosphine compound and silylphosphine compound 日本化学工业株式会社 2022-06-28 CN claimed
EP-3778615-A1 SILYL PHOSPHINE COMPOUND, METHOD FOR PRODUCING SILYL PHOSPHINE COMPOUND AND METHOD FOR FORMING INP QUANTUM DOT Nippon Chemical Industrial Co., Ltd. (JP) 2021-02-17 EP claimed
US-20210002548-A1 SILYL PHOSPHINE COMPOUND, PROCESS FOR PRODUCING SILYL PHOSPHINE COMPOUND AND PROCESS FOR PRODUCING InP QUANTUM DOTS NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2021-01-07 US claimed
CN-111868066-A Silylphosphine compound, method for producing silylphosphine compound, and method for producing InP quantum dot 日本化学工业株式会社 2020-10-30 CN claimed
EP-3521296-B1 SILYL PHOSPHINE COMPOUND MANUFACTURING METHOD AND SILYL PHOSPHINE COMPOUND NIPPON CHEMICAL IND (JP) 2020-10-28 EP claimed
WO-2019188680-A1 SILYL PHOSPHINE COMPOUND, METHOD FOR PRODUCING SILYL PHOSPHINE COMPOUND AND METHOD FOR FORMING InP QUANTUM DOT 日本化学工業株式会社 2019-10-03 WO claimed
US-20190263845-A1 PROCESS FOR PRODUCING SILYL PHOSPHINE COMPOUND AND SILYL PHOSPHINE COMPOUND NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 2019-08-29 US claimed
EP-3521296-A1 SILYL PHOSPHINE COMPOUND MANUFACTURING METHOD AND SILYL PHOSPHINE COMPOUND Nippon Chemical Industrial Co., Ltd. (JP) 2019-08-07 EP claimed
EP-4737444-A1 PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS Gilead Sciences, Inc. (US) 2026-05-06 EP disclosed
US-12410146-B2 Processes and intermediates for preparing MCL1 inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-20250179004-A1 PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS GILEAD SCIENCES, INC. 2025-06-05 US disclosed
US-20250153133-A1 PRODUCTION SYSTEM AND PRODUCTION METHOD FOR FLAVAN OLIGOMER HITACHI PLANT SERVICES CO., LTD. (JP) 2025-05-15 US disclosed
EP-1066303-A1 TRANSITION METAL COMPOUND CONTAINING CATIONIC GROUPS WHICH IS USED AS AN OLEFIN POLYMERIZATION CATALYST COMPONENT Basell Polyolefine GmbH (DE) 2001-01-10 EP disclosed
EP-1066330-A1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF, AND THE UTILIZATION THEREOF FOR THE POLYMERIZATION OF OLEFINS Basell Polyolefine GmbH (DE) 2001-01-10 EP disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed
WO-1999050312-A1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF, AND THE UTILIZATION THEREOF FOR THE POLYMERIZATION OF OLEFINS TARGOR GMBH (DE) 1999-10-07 WO disclosed
WO-1999050274-A1 TRANSITION METAL COMPOUND CONTAINING CATIONIC GROUPS WHICH IS USED AS AN OLEFIN POLYMERIZATION CATALYST COMPONENT TARGOR GMBH (DE) 1999-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410146-B2 Processes and intermediates for preparing MCL1 inhibitors MCL1, BAK1, BCL3 CA2 4374/4885CA1 4227/4885CA9 4438/4885
US-11578266-B2 Silyl phosphine compound, process for producing silyl phosphine compound and process for producing InP quantum dots INPP5B, INPP5A, INPPL1 CA2 1163/4885CA1 1300/4885CA9 754/4885
US-20210002548-A1 SILYL PHOSPHINE COMPOUND, PROCESS FOR PRODUCING SILYL PHOSPHINE COMPOUND AND PROCESS FOR PRODUCING InP QUANTUM DOTS INPP5B, INPP5A, INPPL1 CA2 1163/4885CA1 1300/4885CA9 754/4885
US-20190263845-A1 PROCESS FOR PRODUCING SILYL PHOSPHINE COMPOUND AND SILYL PHOSPHINE COMPOUND SMS, SLK, SRM CA2 845/4885CA1 336/4885CA9 622/4885
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS HAO2, SCO2, SOD1 CA2 524/4885CA1 748/4885CA9 78/4885
US-20250179004-A1 PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS MCL1, BCL3, XIAP CA2 4799/4885CA1 4664/4885CA9 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.