SCHEMBL515972

SCHEMBL515972

CCc1cccc(OC(C)O)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TAAR1 Q96RJ0 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
PTGS2 P35354 1/20 0.43
POLB P06746 2/20 0.43
SOD1 P00441 1/20 0.42
GAA P10253 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
BCL2 P10415 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30333093 1.00 MAPK1 (0.50) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL5245979 0.86 ALOX5 (0.47) TAAR1PPARGPPARA
SCHEMBL1908523 0.85 MAPK1 (0.49) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL516143 0.83 PPARA (0.54) PPARGPPARA
SCHEMBL13463061 0.82 MAPK1 (0.48) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL2319401 0.82 MTNR1A (0.43) MAPK1TSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL8887311 0.81 MAPK1 (0.47) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL4573332 0.81 MAPK1 (0.47) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL26828702 0.81 MAPK1 (0.47) MAPK1L3MBTL1TSHRTDP1TAAR1
SCHEMBL12327116 0.81 MAPK1 (0.47) MAPK1L3MBTL1TSHRTDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605452-B Polyhydroxy aromatic intermediate, preparation method thereof and application of polyhydroxy aromatic intermediate in polycondensate water reducer containing branched side chains 江苏苏博特新材料股份有限公司 2024-06-11 CN claimed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO claimed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US claimed
CN-115605452-A Polyhydroxy aromatic intermediate, preparation method thereof and application thereof in polycondensate water reducing agent containing branched side chain 江苏苏博特新材料股份有限公司(CN) 2023-01-13 CN claimed
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains SOBUTE NEW MATERIALS CO., LTD. (CN) 2026-01-20 US disclosed
CN-115605452-B Polyhydroxy aromatic intermediate, preparation method thereof and application of polyhydroxy aromatic intermediate in polycondensate water reducer containing branched side chains 江苏苏博特新材料股份有限公司 2024-06-11 CN disclosed
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 CN disclosed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO disclosed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US disclosed
CN-115605452-A Polyhydroxy aromatic intermediate, preparation method thereof and application thereof in polycondensate water reducing agent containing branched side chain 江苏苏博特新材料股份有限公司(CN) 2023-01-13 CN disclosed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US disclosed
EP-3747856-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME Teijin Limited (JP) 2020-12-09 EP disclosed
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2020-11-12 US disclosed
CN-111465589-A Compound having fluorene skeleton and method for producing same 帝人株式会社 2020-07-28 CN disclosed
WO-2020085222-A1 CRYSTAL OF COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME 帝人株式会社 2020-04-30 WO disclosed
WO-2019151264-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME 帝人株式会社 2019-08-08 WO disclosed
US-8841491-B2 Method for producing fluorene derivative TAOKA CHEMICAL CO., LTD. (JP) 2014-09-23 US disclosed
CN-102388012-A Method for producing fluorene derivative TAOKA CHEMICAL CO LTD 2012-03-21 CN disclosed
EP-2420485-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE Taoka Chemical Co., Ltd. (JP) 2012-02-22 EP disclosed
US-20120029244-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE TAOKA CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME RFT1, AFF1, RER1 MAPK1 301/4885L3MBTL1 2950/4885TSHR 2403/4885
US-20120029244-A1 METHOD FOR PRODUCING FLUORENE DERIVATIVE ADH1A, AFF2, AFF1 MAPK1 1479/4885L3MBTL1 4726/4885TSHR 1365/4885
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 MAPK1 301/4885L3MBTL1 2950/4885TSHR 2403/4885
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains IPMK, GRHPR, PIEZO1 MAPK1 1655/4885L3MBTL1 1517/4885TSHR 4636/4885
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BICRA, GRHPR, SMARCC2 MAPK1 3422/4885L3MBTL1 2343/4885TSHR 4571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.