Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257571 | 0.94 | PPARA (0.66) | PPARAPPARGCYP2D6CNR1CNR2 | |
| SCHEMBL11320800 | 0.94 | PPARA (0.66) | PPARAPPARGCYP2D6CNR1CNR2 | |
| SCHEMBL4568880 | 0.94 | PPARA (0.57) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL4568872 | 0.92 | PPARA (0.56) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL4568893 | 0.91 | PPARA (0.58) | PPARAPPARGCYP2D6KCNH2CNR1 | |
| SCHEMBL5245986 | 0.90 | CYP4F2 (0.54) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL4341923 | 0.90 | CYP4F2 (0.57) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL15016678 | 0.89 | PPARA (0.59) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL3025896 | 0.89 | CYP4F2 (0.61) | PPARAPPARGCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL4568871 | 0.88 | PPARA (0.61) | PPARAPPARGCYP2D6KCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| CN-111465589-B | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2024-01-05 | — | — | CN | disclosed |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | TEIJIN LIMITED (JP) | 2022-05-24 | — | — | US | disclosed |
| EP-3747856-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | Teijin Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | TEIJIN LIMITED (JP) | 2020-11-12 | — | — | US | disclosed |
| CN-111465589-A | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2020-07-28 | — | — | CN | disclosed |
| US-10167266-B2 | Sodium channel blockers | PARION SCIENCES, INC. (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180177746-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2018-06-28 | — | — | US | disclosed |
| US-20170267650-A1 | SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-9737496-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20130197096-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20120270769-A1 | METHODS OF USING MACROCYCLIC INHIBITORS OF SERINE PROTEASE ENZYMES | TRANZYME PHARMA INC. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-20120270807-A1 | MACROCYCLIC INHIBITORS OF SERINE PROTEASE ENZYMES | TRANZYME PHARMA INC. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-20120214852-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120129894-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-05-17 | — | — | US | disclosed |
| CN-102388012-A | Method for producing fluorene derivative | TAOKA CHEMICAL CO LTD | 2012-03-21 | — | — | CN | disclosed |
| EP-2420485-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | Taoka Chemical Co., Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | TAOKA CHEMICAL CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-7982071-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2011-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-20170267650-A1 | SODIUM CHANNEL BLOCKERS | HCN4, SCN2B, SCN5A | PPARA 3375/4885PPARG 4282/4885CYP2D6 2925/4885 |
| US-10167266-B2 | Sodium channel blockers | SCNN1B, SCNN1A, SCNN1G | PPARA 2857/4885PPARG 2793/4885CYP2D6 3007/4885 |
| US-20120270769-A1 | METHODS OF USING MACROCYCLIC INHIBITORS OF SERINE PROTEASE ENZYMES | PRSS1, SPINT2, TMPRSS15 | PPARA 4577/4885PPARG 4622/4885CYP2D6 1394/4885 |
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | RFT1, AFF1, RER1 | PPARA 1428/4885PPARG 2369/4885CYP2D6 3183/4885 |
| US-20120029244-A1 | METHOD FOR PRODUCING FLUORENE DERIVATIVE | ADH1A, AFF2, AFF1 | PPARA 124/4885PPARG 159/4885CYP2D6 365/4885 |
| US-20130197096-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | RFT1, AFF1, RER1 | PPARA 1428/4885PPARG 2369/4885CYP2D6 3183/4885 |
| US-20120214852-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-20180177746-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-20120129894-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | PPARA 586/4885PPARG 136/4885CYP2D6 3691/4885 |
| US-20120270807-A1 | MACROCYCLIC INHIBITORS OF SERINE PROTEASE ENZYMES | PRSS1, SPINT2, SERPINB1 | PPARA 4539/4885PPARG 4502/4885CYP2D6 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.