SCHEMBL7961503

SCHEMBL7961503

CCCCCNc1cccnc1NS(N)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TLR8 Q9NR97 1/20 0.41
TLR7 Q9NYK1 1/20 0.41
CISD1 Q9NZ45 6/20 0.41
UTS2R Q9UKP6 3/20 0.40
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
GLO1 Q04760 1/20 0.38
S1PR2 O95136 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9573464 0.89 L3MBTL1 (0.42) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL516228 0.84 UTS2R (0.49) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL7961505 0.82 L3MBTL1 (0.43) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL24846448 0.81 UTS2R (0.44) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL9022013 0.77 POLB (0.45) L3MBTL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL4711248 0.76 BACE1 (0.53) L3MBTL1TLR8TLR7UTS2RS1PR2
SCHEMBL8510590 0.76 L3MBTL1 (0.45) L3MBTL1TLR8TLR7UTS2RS1PR2
SCHEMBL27807223 0.73 ALDH1A1 (0.49) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL11666498 0.73 NPC1 (0.42) L3MBTL1TLR8TLR7UTS2RS1PR2
SCHEMBL27660967 0.72 NPC1 (0.48) L3MBTL1KDM4ETLR8TLR7UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US claimed
US-6316388-B1 ANTIGROWTH AGENTS FOR PLANTS HOECHST SCHERING AGREVO GMBH (DE) 2001-11-13 US disclosed
US-5847146-A N-heteroartyl-n'-(pyrid-2yl-sulfonyl) ureas, processes for their preparation, and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1998-12-08 US disclosed