SCHEMBL5162966

SCHEMBL5162966

CCCCc1occc1S

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CTRC Q99895 1/20 0.31
CA1 P00915 1/20 0.31
PTPN1 P18031 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5162410 0.87
SCHEMBL5164012 0.78
SCHEMBL9769033 0.77 SKP2 (0.37) CA2SMN1; SMN2CTRCCA1PTPN1
SCHEMBL9769026 0.75 CA2 (0.32) CA2SMN1; SMN2CTRCCA1PTPN1
SCHEMBL27825754 0.75 CA2 (0.30) CA2SMN1; SMN2
SCHEMBL3933030 0.71 CTRC (0.38) CA2CTRCCA1PDE4APDE4B
SCHEMBL27823063 0.71 LIPG (0.40) CA2CTRC
SCHEMBL3919456 0.71 ALDH1A1 (0.36) CA2SMN1; SMN2
SCHEMBL31265933 0.71 KDM4E (0.37) CA2SMN1; SMN2CTRC
SCHEMBL26972082 0.69 HSD11B1 (0.35) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4293579-A Flavoring with 3,5-di-(2-methylpropyl)-1,2,4-trithiolane INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-06 US claimed
US-4041186-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-09 US claimed
US-4031256-A ORGANOLEPTIC, NUTTY TASTE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US claimed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US claimed
EP-1276391-B1 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC (US) 2007-03-07 EP disclosed
EP-1276391-A4 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC (US) 2005-11-09 EP disclosed
US-6899911-B2 Ethyl 4-(thioacetoxy)butyrate as a flavoring agent and methods for preparing and using same INTERNATIONAL FLAVORS & FRAGRANCES, INC. 2005-05-31 US disclosed
EP-1276391-A1 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME Bush Boake Allen Inc. (US) 2003-01-22 EP disclosed
US-20020090435-A1 Ethyl 4-(thioacetoxy)butyrate as a flavoring agent and methods for preparing and using same BUSH BOAKE ALLEN INC. 2002-07-11 US disclosed
WO-2001076389-A1 ETHYL 4-(THIOACETOXY)BUTYRATE AS A FLAVORING AGENT AND METHODS FOR PREPARING AND USING SAME BUSH BOAKE ALLEN INC. (US) 2001-10-18 WO disclosed
US-4293579-A Flavoring with 3,5-di-(2-methylpropyl)-1,2,4-trithiolane INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-06 US disclosed
US-4263331-A FOODS, HAZELNUT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-04-21 US disclosed
US-4259507-A ROAST PORK FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-31 US disclosed
US-4055578-A FLAVORS, ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-25 US disclosed
US-4041186-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-09 US disclosed
US-4031256-A ORGANOLEPTIC, NUTTY TASTE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US disclosed
US-4020175-A MEAT AROMA AND FLAVOR INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-04-26 US disclosed
US-4007287-A Flavoring with (allyl)(2-methyl-3-furyl) sulfide INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-02-08 US disclosed
US-3988510-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-26 US disclosed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US disclosed