Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769033 | 0.77 | SKP2 (0.37) | CA2SMN1; SMN2CTRCCA1PTPN1 | |
| SCHEMBL5162966 | 0.75 | CA2 (0.32) | CA2SMN1; SMN2CTRCCA1PTPN1 | |
| SCHEMBL3933030 | 0.71 | CTRC (0.38) | CA2CTRCCA1PDE4APDE4B | |
| SCHEMBL27823063 | 0.71 | LIPG (0.40) | CA2CTRC | |
| SCHEMBL3919456 | 0.71 | ALDH1A1 (0.36) | CA2SMN1; SMN2THRB | |
| SCHEMBL31265933 | 0.71 | KDM4E (0.37) | CA2SMN1; SMN2CTRC | |
| SCHEMBL27825754 | 0.71 | CA2 (0.30) | CA2SMN1; SMN2 | |
| SCHEMBL18598997 | 0.69 | ALDH1A1 (0.42) | SMN1; SMN2PTPN1 | |
| SCHEMBL9625506 | 0.69 | KDM4E (0.48) | CTRCPTPN1 | |
| SCHEMBL13806459 | 0.69 | GABRA1 (0.33) | SMN1; SMN2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |