SCHEMBL5164451

SCHEMBL5164451

CCC(=O)N(c1ccccc1)C1CCN(C)CC1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 9/20 0.72
OPRD1 P41143 4/20 0.72
SIGMAR1 Q99720 2/20 0.72
SLC22A1 O15245 1/20 0.72
NR1I2 O75469 1/20 0.72
ABCB1 P08183 1/20 0.72
CHRM1 P11229 1/20 0.72
DRD2 P14416 1/20 0.72
ADRA2B P18089 1/20 0.72
ADRA2C P18825 1/20 0.72
CHRM3 P20309 1/20 0.72
MAOA P21397 1/20 0.72
DRD4 P21917 1/20 0.72
MAOB P27338 1/20 0.72
ADRA1A P35348 1/20 0.72
HRH1 P35367 1/20 0.72
ADRA1B P35368 1/20 0.72
DRD3 P35462 1/20 0.72
OPRK1 P41145 1/20 0.72
CHRNA4 P43681 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20926854 0.88 OPRM1 (0.71) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL23823806 0.87 OPRM1 (0.79) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL14252397 0.87 OPRM1 (0.70) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL23651692 0.87 OPRM1 (0.78) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL13116886 0.87 OPRM1 (0.70) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL8565516 0.86 OPRM1 (0.77) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL23651683 0.86 OPRM1 (0.76) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL20916018 0.86 OPRM1 (0.68) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL24801394 0.85 OPRM1 (0.76) OPRM1OPRD1SIGMAR1SLC22A1NR1I2
SCHEMBL8831680 0.85 OPRM1 (0.76) OPRM1OPRD1SIGMAR1SLC22A1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036595-A Fentanyl hapten, complete antigen thereof and application thereof 中国药科大学 2026-05-15 CN claimed
CN-119291192-A Kit for detecting content of fentanyl and analogues thereof and application of kit 中国药科大学 2025-01-10 CN claimed
CN-122036595-A Fentanyl hapten, complete antigen thereof and application thereof 中国药科大学 2026-05-15 CN disclosed
WO-2025094145-A1 INTEGRATED SINGLE USE TEST KITS FOR DRUG CHECKING ENOCIAL AKTIEBOLAG (SE) 2025-05-08 WO disclosed
US-20140179686-A1 Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations GRUENENTHAL GMBH (DE) 2014-06-26 US disclosed
US-8710233-B2 Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations GRUENENTHAL GMBH (DE) 2014-04-29 US disclosed
US-20100273765-A1 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. 2010-10-28 US disclosed
CN-100402084-C Method for detection or quantitative determination of metabolite of fentanyl or metabolite of fentanyl analogues and kit LANDAUKES LAB CO LTD (GB) 2008-07-16 CN disclosed
US-7271165-B2 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. (US) 2007-09-18 US disclosed
US-20070142392-A1 Uses of rifamycins ACTIVBIOTICS, INC. (US) 2007-06-21 US disclosed
US-20070105861-A1 NOVEL VANILLOID RECEPTOR LIGANDS AND USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS GRUENENTHAL GMBH (DE) 2007-05-10 US disclosed
EP-1312923-B1 Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs RANDOX LAB LTD (GB) 2007-03-28 EP disclosed
US-7109310-B2 Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs RANDOX LABORATORIES, LTD. (IE) 2006-09-19 US disclosed
US-20030170728-A1 Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs RANDOX LABORATORIES LIMITED 2003-09-11 US disclosed
CN-1428607-A Method for detection or quantitative determination of metabolite of fentanyl or metabolite of fentanyl analogues and kit LANDAUKES LAB CO LTD (GB) 2003-07-09 CN disclosed
EP-1312923-A2 Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs Randox Laboratories Ltd. (GB) 2003-05-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105861-A1 NOVEL VANILLOID RECEPTOR LIGANDS AND USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS TRPV1, TRPV5, TRPV2 OPRM1 137/4885OPRD1 97/4885SIGMAR1 180/4885
US-20070142392-A1 Uses of rifamycins TNF, TLR6, IL6 OPRM1 2041/4885OPRD1 2983/4885SIGMAR1 1528/4885
US-20100273765-A1 Rifamycin analogs and uses thereof RIF1, HDAC5, AADAC OPRM1 3207/4885OPRD1 3678/4885SIGMAR1 2370/4885
US-20030170728-A1 Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs OPRK1, KIT, OPRM1 OPRM1 3/4885OPRD1 14/4885SIGMAR1 262/4885
US-20140179686-A1 Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations TRPV1, TRPV5, TRPV2 OPRM1 137/4885OPRD1 97/4885SIGMAR1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.