Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453949 | 0.96 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL7050763 | 0.86 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL2970565 | 0.77 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7630825 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL5859366 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7559465 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9068321 | 0.75 | BCHE (0.36) | — | |
| SCHEMBL27459604 | 0.75 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL27484580 | 0.74 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7937296 | 0.73 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247686-B2 | Solid cocatalyst component for olefin polymerization and catalyst system thereof | BASELL POLYOLEFINE GMBH (DE) | 2007-07-24 | — | — | US | disclosed |
| EP-1442067-B1 | SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF | SUNALLOMER LTD (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-20050009689-A1 | Solid cocatalyst component for olefin polymerization and catalyst system thereof | SUNALLOMER LTD. (JP) | 2005-01-13 | — | — | US | disclosed |