Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416585 | 1.00 | IDO1 (0.36) | IDO1DHODHEGLN1NAMPTGCK | |
| SCHEMBL195661 | 0.95 | IDO1 (0.36) | IDO1DHODHEGLN1NAMPTGCK | |
| SCHEMBL29416604 | 0.95 | IDO1 (0.36) | IDO1DHODHEGLN1NAMPTGCK | |
| SCHEMBL29416635 | 0.93 | EGLN1 (0.39) | IDO1DHODHEGLN1NAMPTGCK | |
| SCHEMBL195408 | 0.93 | EGLN1 (0.39) | IDO1DHODHEGLN1NAMPTGCK | |
| SCHEMBL29416636 | 0.91 | IDO1 (0.38) | IDO1DHODHNAMPTMALT1CNR1 | |
| SCHEMBL29355401 | 0.91 | IDO1 (0.38) | IDO1DHODHNAMPTMALT1CNR1 | |
| SCHEMBL27174182 | 0.91 | IDO1 (0.38) | IDO1DHODHNAMPTMALT1CNR1 | |
| SCHEMBL230723 | 0.91 | IDO1 (0.38) | IDO1DHODHNAMPTMALT1CNR1 | |
| SCHEMBL4553452 | 0.89 | IDO1 (0.42) | IDO1DHODHNAMPTMALT1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011527307-A | — | — | 2011-10-27 | — | — | JP | claimed |
| US-20110224075-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2011-09-15 | — | — | US | claimed |
| US-20110118212-A1 | Pestcidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2011-05-19 | — | — | US | claimed |
| EP-2306837-A1 | PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I | BASF SE (DE) | 2011-04-13 | — | — | EP | claimed |
| CN-114573573-A | Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-109068651-B | Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2022-03-01 | — | — | CN | disclosed |
| US-10231455-B2 | Pesticidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2019-03-19 | — | — | US | disclosed |
| US-20180007904-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | BASF SE (DE) | 2018-01-11 | — | — | US | disclosed |
| US-8716182-B2 | Liquid aqueous crop protection formulations | BASF SE (DE) | 2014-05-06 | — | — | US | disclosed |
| US-8563474-B2 | Pestcidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2013-10-22 | — | — | US | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| US-8221775-B2 | Pyrrolin-2-ylamino compounds for combating animal pests | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20110224075-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110195839-A1 | Liquid Aqueous Crop Protection Formulations | BASF SE (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20110173726-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | BASF SE (DE) | 2011-06-30 | — | — | US | disclosed |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | BASF SE | 2011-06-30 | — | — | US | disclosed |
| EP-2329711-A1 | Novel seed treatment method by using supercritical carbon dioxide | BASF SE (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110118212-A1 | Pestcidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | PRDX1, PRDX2, PRDX5 | IDO1 59/4885DHODH 4196/4885EGLN1 386/4885 |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | GRIN2A, NR2C2, GRIA2 | IDO1 1420/4885DHODH 2526/4885EGLN1 3921/4885 |
| US-20110160269-A1 | Pyrrolin-2-ylamino Compounds For Combating Animal Pests | RXFP3, CBR3, ATL3 | IDO1 290/4885DHODH 3466/4885EGLN1 376/4885 |
| US-20110195839-A1 | Liquid Aqueous Crop Protection Formulations | AQP1, GANC, BROX | IDO1 1388/4885DHODH 3203/4885EGLN1 1684/4885 |
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | IDO1 1514/4885DHODH 4254/4885EGLN1 1324/4885 |
| US-20110224075-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | CBR3, AOC3, MT-CO3 | IDO1 428/4885DHODH 2236/4885EGLN1 2941/4885 |
| US-20110173726-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | PRXL2A, GRIN2C, GRIN2A | IDO1 1363/4885DHODH 3553/4885EGLN1 1566/4885 |
| US-20110118212-A1 | Pestcidal active mixtures comprising isoxazoline compounds I | CHRM3, CHRM5, CHRM1 | IDO1 705/4885DHODH 4306/4885EGLN1 3203/4885 |
| US-20180007904-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | CHRM3, CHRM5, CACNA1C | IDO1 585/4885DHODH 4267/4885EGLN1 3214/4885 |
| US-10231455-B2 | Pesticidal active mixtures comprising isoxazoline compounds I | CHRM3, CHRM5, CACNA1C | IDO1 585/4885DHODH 4267/4885EGLN1 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.