Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | NPC1 | O15118 | 10/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032426 | 0.85 | RAB9A (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9547503 | 0.83 | RAB9A (0.89) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3072886 | 0.82 | RAB9A (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3608965 | 0.82 | RAB9A (0.67) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL1672113 | 0.82 | RAB9A (0.72) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3294926 | 0.81 | KDM4E (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL15601787 | 0.81 | KIF11 (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8596702 | 0.81 | RAB9A (0.71) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL6409623 | 0.80 | RAB9A (0.56) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL651822 | 0.80 | ALDH1A1 (0.61) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836485-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | Polyphor Ag (CH) | 2015-02-18 | — | — | EP | claimed |
| WO-2013139697-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2013-09-26 | — | — | WO | claimed |
| CN-101108813-B | Method of manufacturing 1-(2-methoxyphenyl)-3-naphthyl group-2-urea | LUOYANG PULIKE BIOLOGY ENGINEERING CO LTD | 2010-05-12 | — | — | CN | claimed |
| CN-101108813-A | Method of manufacturing 1-(2-methoxyphenyl)-3-naphthyl group-2-urea | LUOYANG PULIKE BIOLOGY ENGINEE (CN) | 2008-01-23 | — | — | CN | claimed |
| EP-1828169-A2 | UREA INHIBITORS OF MAP KINASES | Locus Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006062982-A2 | UREA INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |
| JP-2004534046-A | — | — | 2004-11-11 | — | — | JP | claimed |
| CN-119452084-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119317632-A | Oligonucleotide compositions and methods relating thereto | 波涛生命科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-12145913-B2 | Inhibition of Olig2 activity | Curtana Pharmaceuticals, Inc. (US) | 2024-11-19 | — | — | US | disclosed |
| CN-117003802-B | Sulfonamide derivative containing glucosamine as well as preparation method and application thereof | 沈阳药科大学 | 2024-08-13 | — | — | CN | disclosed |
| EP-4404942-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| CN-117447399-A | Naphthalene formylhydrazine compound and preparation method and application thereof | 上海应用技术大学 | 2024-01-26 | — | — | CN | disclosed |
| US-4891069-A | CATALYST FOR REDUCTION OF METAL COMPOUND BY GENERATED HYDROGEN | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1990-01-02 | — | — | US | disclosed |
| US-4816070-A | PRINTED CIRCUITS, ADHESION | TECHO INSTRUMENTS INVESTMENTS LTD. (IL) | 1989-03-28 | — | — | US | disclosed |
| US-4790912-A | ELECTROLYTICALLY-GENERATED HYDROGEN AND CATALYST CONVERT METAL SALT IN BATH TO METAL | TECHNO-INSTRUMENTS INVESTMENTS LTD. (IL) | 1988-12-13 | — | — | US | disclosed |
| US-4749449-A | PLATING ON CATALYZED THROUGH HOLE WALL IN PATTERENED CONDUCTIVE AND INSULATING LAYERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4715894-A | AMINIMIZATION OF SMEAR | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-12-29 | — | — | US | disclosed |
| US-4657632-A | CONTAINING A THIOUREA AND A UREA COMPOUND | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-04-14 | — | — | US | disclosed |
| EP-0216531-A1 | Use of immersion tin and tin alloys as a bonding medium for multilayer circuits | TECHNO INSTRUMENTS INVESTMENTS 1983 LTD. (IL) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12145913-B2 | Inhibition of Olig2 activity | POU2F2, POU2F1, PLP2 | RAB9A 3701/4885NPC1 4540/4885MAPT 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.