Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132395 | 0.98 | CYP19A1 (0.55) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL516961 | 0.84 | NPC1 (0.59) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL27915152 | 0.84 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL4147377 | 0.84 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL1911780 | 0.84 | CA1 (0.70) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL9818507 | 0.83 | CA2 (0.72) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL4158621 | 0.76 | CA12 (0.51) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL12124985 | 0.75 | NPC1 (0.75) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6741892 | 0.75 | CYP19A1 (0.64) | CYP19A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL27457724 | 0.75 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789118-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2017-10-17 | — | — | US | disclosed |
| US-9789118-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2017-10-17 | — | — | US | disclosed |
| US-9789118-B2 | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof | NOVARTIS AG (CH) | 2017-10-17 | — | — | US | disclosed |
| EP-2598486-B1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS | NOVARTIS AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| EP-2598486-B1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS | NOVARTIS AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| US-20140227208-A1 | COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING MECHANICALLY-INDUCED SKIN INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140227208-A1 | COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING MECHANICALLY-INDUCED SKIN INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140171363-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| US-20140171363-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| US-20140171363-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| EP-0121495-B1 | MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |
| EP-0133270-A1 | Reactive dyes | BASF Aktiengesellschaft (DE) | 1985-02-20 | — | — | EP | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |
| EP-0119441-A2 | Reactive dyes with substituted 4-fluoropyridaz-6-one groups | BASF Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |
| EP-0031099-B1 | COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0031099-A2 | Compounds with reactive rests and their use in dyeing fibres | BASF Aktiengesellschaft (DE) | 1981-07-01 | — | — | EP | disclosed |
| EP-0013609-A1 | Water-soluble monoazo dyes of the benzene azo indole series, their preparation and their application for the colouration of polyamide textile materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-07-23 | — | — | EP | disclosed |
| US-4058517-A | Preparation of a concentrated solution of an anionic azo dye containing a sulfonic acid group | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3956267-A | Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171363-A1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF | ACACA, ACACB, COASY | CYP19A1 359/4885NPC1 274/4885RAB9A 4359/4885 |
| US-20140227208-A1 | COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING MECHANICALLY-INDUCED SKIN INFLAMMATION | CUTA, KRT18, IL33 | CYP19A1 355/4885NPC1 4716/4885RAB9A 4806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.