SCHEMBL5175358

SCHEMBL5175358

CCCCCCCC/C=C\CCCCCCCCN(C=O)CCCCCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.59
TRPV1 Q8NER1 2/20 0.59
TSHR P16473 1/20 0.48
EPHX2 P34913 3/20 0.47
TERT O14746 3/20 0.47
PTPN1 P18031 3/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 2/20 0.47
BLM P54132 2/20 0.47
HSD17B10 Q99714 2/20 0.47
FABP4 P15090 2/20 0.47
KMT2A Q03164 2/20 0.47
GMNN O75496 1/20 0.47
USP2 O75604 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174206 1.00 FAAH (0.59) FAAHTRPV1TSHREPHX2TERT
SCHEMBL5174196 1.00 FAAH (0.59) FAAHTRPV1TSHREPHX2TERT
SCHEMBL5171649 1.00 FAAH (0.59) FAAHTRPV1TSHREPHX2TERT
Hydrochloric Acid SCHEMBL20840339 0.98 FAAH (0.57) FAAHTRPV1TSHREPHX2TERT
SCHEMBL95389 0.89 ADH1C (0.52) FAAHTRPV1TSHR
SCHEMBL5175186 0.89 ADH1C (0.52) FAAHTRPV1TSHR
SCHEMBL3962903 0.89 ADH1C (0.52) FAAHTRPV1TSHR
SCHEMBL276871 0.89 ADH1C (0.52) FAAHTRPV1TSHR
SCHEMBL277587 0.89 ADH1C (0.52) FAAHTRPV1TSHR
SCHEMBL55195 0.89 ADH1C (0.52) FAAHTRPV1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299003-B2 Composition comprising a sulfur-containing, phosphorus-containing compound, and/or its salt, and uses thereof AFTON CHEMICAL CORPORATION (US) 2012-10-30 US disclosed
EP-1832646-A1 Lubricant composition Afton Chemical Corporation (US) 2007-09-12 EP disclosed
US-20070142249-A1 Composition comprising a sulfur-containing, phosphorus-containing compound, and/or its salt, and uses threof AFTON CHEMICAL CORPORATION 2007-06-21 US disclosed
US-20070142659-A1 Sulfur-containing, phosphorus-containing compound, its salt, and methods thereof AFTON CHEMICAL CORPORATION 2007-06-21 US disclosed
US-20070142248-A1 Viscosity index improver, and a sterically hindered sulfur-containing, phosphorus-containing compound and a salt of the thiophosphate AFTON CHEMICAL CORPORATION 2007-06-21 US disclosed
US-20070142237-A1 Lubricant composition AFTON CHEMICAL CORPORATION 2007-06-21 US disclosed
EP-1785476-A1 Lubricant composition Afton Chemical Corporation (US) 2007-05-16 EP disclosed
EP-1785471-A1 A salt of sulfur-containing, phosphorus-containing compound, and method of preparation thereof Afton Chemical Corporation (US) 2007-05-16 EP disclosed
EP-1785475-A1 A gear additive composition Afton Chemical Corporation (US) 2007-05-16 EP disclosed
EP-1785474-A1 Lubricant composition Afton Chemical Corporation (US) 2007-05-16 EP disclosed
EP-1785470-A2 Composition comprising a sulfur-containing, phosphorus-containing compound, and/or its salt, and uses thereof Afton Chemical Corporation (US) 2007-05-16 EP disclosed
US-20070105729-A1 Gear additive composition AFTON CHEMICAL CORPORATION 2007-05-10 US disclosed
US-20070105728-A1 Lubricant composition AFTON CHEMICAL CORPORATION 2007-05-10 US disclosed
EP-0445243-B1 A METHOD OF PREPARING MONOTHIOPHOSPHORIC ACID BY SULFURIZING A PHOSPHITE IN THE PRESENCE OF AN AMIDE LUBRIZOL CORP (US) 1995-02-15 EP disclosed
EP-0445243-A1 A METHOD OF PREPARING MONOTHIOPHOSPHORIC ACID BY SULFURIZING A PHOSPHITE IN THE PRESENCE OF AN AMIDE. LUBRIZOL CORP (US) 1991-09-11 EP disclosed
WO-1991004979-A1 A METHOD OF PREPARING MONOTHIOPHOSPHORIC ACID BY SULFURIZING A PHOSPHITE IN THE PRESENCE OF AN AMIDE THE LUBRIZOL CORPORATION (US) 1991-04-18 WO disclosed
US-4997968-A Sulfiding phosphonate THE LUBRIZOL CORPORATION (US) 1991-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142248-A1 Viscosity index improver, and a sterically hindered sulfur-containing, phosphorus-containing compound and a salt of the thiophosphate PSPH, PHOSPHO1, SOST FAAH 4319/4885TRPV1 2651/4885TSHR 760/4885
US-20070142249-A1 Composition comprising a sulfur-containing, phosphorus-containing compound, and/or its salt, and uses threof SRSF9, SLC6A9, SLC9A3 FAAH 4765/4885TRPV1 1478/4885TSHR 1510/4885
US-20070142659-A1 Sulfur-containing, phosphorus-containing compound, its salt, and methods thereof TST, PSPH, SCLY FAAH 4488/4885TRPV1 2341/4885TSHR 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.